摘要
目的：评价危重患者抢救性气管插管时给予适当镇静剂的意义。方法：60例抢救性气管插管的危重患者随机分为对照组（不予任何镇静剂），咪唑安定组[咪唑安定（0．03～0．05）mg／kg]和异丙酚组[异丙酚（0．5～1．0）mg／kg]。记录3组插管前。插管后1、5min的血流动力学指标及心肌耗氧变化。结果：3组插管前，插管后1、5min的血流动力学指标及心肌耗氧变化有统计学意义（P〈0．05）。但spO2比无统计学意义。结论：小剂量异丙酚和咪唑安定用于抢救性气管插管安全、有效。
Objective： To evaluate the effects of low-dose sedatives on emergent endotracheal intubation. Methods： Sixty patients with emergent endotmcheal intubation were randomly divided into control group（no sedative before intubation ）, midazolam group [midazolam （0.03～0.05） mg/kg ] and propofol group [ propofol （0.5 ～ 1.0 ） mg/kg ]. The hemodynamic indexes and myocardial oxygen consumption were monitored among groups before intubation and 1, 5 minutes after intubation, respectively. Results： There were statistical significance in hemodynamic indexes and myocardial oxygen comsumption among groups（ P 〈 0.05）. SpO2 levels had no significant differences among groups. Conclusion： Low-dose propofol and midazolam are safe and effective in emergent endotracheal intubation for crisis patients.
出处
《汕头大学医学院学报》
2008年第2期98-99,共2页
Journal of Shantou University Medical College
关键词
气管插管
咪唑安定
异丙酚
endotracheal intubation
midazolam
propotol
