摘要
为了解顺序联合膀胱灌注预防膀胱癌术后复发的疗效,自1991年6月~1997年2月,用噻替哌60mg、卡铂400mg、阿霉素40mg加异博定10mg顺序联合膀胱灌注膀胱癌患者68例,每周一种药物共6周,以后每个月一种药物持续至术后2年,随访10个月~5年5个月,平均3年5个月。结果T1和T2肿瘤者无1例复发,副作用轻。结果表明,多药序联膀胱灌注疗效优于单药灌注。
For the prevention of tumor recurrence, from June 1991 to Feb. 1997, sequential intravesical instillation of adriamycin(40mg) and verapamil (10mg) combined with thioTEPA(60mg),carboplatin (400mg) was carried out for 68 cases of bladder carcinoma after surgery. The average follow up period was 3 years and five months. No recurrence has been observed in all the 62 cases of stage T1 and T2 tumors. Side effects were mild. It might be an effective means of preventing drug resistance and recurrence of bladder tumor.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
1997年第12期735-735,共1页
Chinese Journal of Urology