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黄芪注射液联合IL-2改善大肠癌患者免疫功能研究 被引量:7

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摘要 目的:观察黄芪注射液联合重组人白细胞介素2对术后化疗后大肠癌患者免疫功能的影响。方法:47例患者随机分为3组,分别给予黄芪注射液、重组人白细胞介素-2、黄芪注射液联合重组人白细胞介素-2,观测治疗前后患者症状、生存质量、T细胞亚群、NK数量等变化。结果:黄芪注射液可以缓解大肠癌术后化疗后患者的症状,改善生存质量,提高受到抑制的CD3、CD4、CD8以及NK细胞的数量;IL-2可以提高大肠癌术后化疗后患者CD3、CD8以及NK细胞的数量。黄芪注射液联合IL-2可以达到协同的作用。结论:黄芪注射液联合IL-2可以用于大肠癌患者手术化疗后免疫功能低下的治疗。
出处 《中药药理与临床》 CAS CSCD 北大核心 2008年第2期99-101,共3页 Pharmacology and Clinics of Chinese Materia Medica
基金 上海市科委攻关计划(064119625) 上海市卫生局科教处项目(2006095) 上海市重点学科建设项目(Y0302)
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