摘要
探讨胃粘膜淋巴滤泡与幽门螺杆菌感染之间的关系。４０９例胃镜检查患者作胃粘膜幽门螺杆菌培养、组织病理学检查，并进行病例对照研究。结果：胃粘膜内淋巴滤泡的出现与幽门螺杆菌感染有显著相关性，比数比为３．１（９５％ＣＩ为２．１～４．８），出现≥３个淋巴滤泡时比数比则为７．７（９５％ＣＩ为２．５～２３．４），且不受患者年龄、性别的影响。淋巴滤泡与其它组织病理学改变：炎症程度、炎症活动性及萎缩性改变有显著相关性，与肠化生则无相关性。提示幽门螺杆菌感染可能是胃粘膜内淋巴滤泡形成的主要原因。
The relationship between gastric lymphoid follicles and helicobacter pylori(Hp) infection was studied. 409 cases of patients underwent gastroendoscopy and gastric mucosal biopsy specimens were taken for Hp cultre and histopathologic examination. Statistical analysis showed significant correlativity between lymphoid follicles and Hp infection. The odd rate(OR) was 3.1(OR 95% CI=2.1￣4.8),when number of lymphoid follicles≥3, OR=7.7(OR 95%CI=2.5￣23.4). It was not influenced by patient′s sex and age. The prevalence of lymphoid follicles depended on the degree of inflammation, activity of the gastritis and atrophy, but did not correlate with intestinal metaplasia. Hp infection may be an important cause of formation of gastric lymphoid follicles.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
1997年第6期593-596,共4页
Journal of Nanjing Medical University(Natural Sciences)
