摘要
目的：观察果糖二磷酸钠（ＦＤＰ）治疗急性脑梗死的疗效及不良反应。方法：将８０例经ＣＴ或ＭＲＩ证实的急性脑梗死病人随机分为２组。ＦＤＰ组４０例（男性２６例，女性１４例；年龄６４±ｓ１７ａ）用ＦＤＰ２０ｇ，静脉滴注ｑｄ×２０ｄ。对照组４０例（男性２８例，女性１２例；年龄６７±１７ａ）用右旋糖酐－４０葡萄糖注射液５００ｍＬ加复方丹参注射液２０ｍＬ，静脉滴注ｑｄ×２１ｄ。结果：ＦＤＰ组总有效率为７８％，对照组总有效率为５３％，Ｐ＜０．０５。治疗期间未发现任何不良反应。结论：ＦＤＰ治疗急性脑梗死是安全、有效的。
AIM: To study the efficacy and adverse reactions of fructose sodium diphosphate (FDP) on patients with acute cerebral infarction. METHODS: The 80 acute cerebral infarction patients diagnosed by CT or MRI were divided at random into 2 groups:40 patients (M 26, F 14; age 64±s 17 a) received FDP 20 g, iv, drip, qd for 20 d. The other 40 patients (M 28, F 12; age 67±17 a) received compound Salvia miltiorrhiza 20 mL in dextran 40 glucose injection 500 mL, iv, drip, qd for 21 d. RESULTS: The total effective rates of FDP group and control gorup for acute cerebral infarction were 78% and 53%, respectively (P<0.05). No adverse effects were found. CONCLUSION: FDP is safe and useful for the treatment of acute cerebral infarction.
出处
《新药与临床》
CSCD
北大核心
1997年第6期347-348,共2页
关键词
果糖二磷酸盐
脑梗塞
药物疗法
cerebral infarction
fructosediphosphates
Salvia miltiorrhiza
dextrans
