摘要
用核素心室造影法评价了心脏病病人口服硝苯啶(NIF,20mg、31例)和地尔硫(艹卓)(DIL,60mg、24例)前后血流动力学参数的变化。口服NIF后左心功能显著改善,LVEF自0.56增至0.63(P<0.001),LVEDV增加15ml/m^2(P<0.01),CO与CI分别增加2.01L/min和1.23L/min/m^2(P均<0.001)。而口服DIL后左心功能仅轻度改善,LVEF和LVEDV仅分别增加0.03和5ml/m^2。在陈旧性心肌梗塞病人,无论NIF或DIL均未见心功能的改善。
Hemodynamic parameters were assessed before and 0.5h after the p. o. of 20mg of nifedipine(NIF) in 31 patients and 60 mg of diltiazem(DIL) in 24 patients with radio-nuclide ventriculography. After oraltherapy.NZF improved the LV pumping fucntion, LVEF increased from 0.56 to 0.63 (P<0.001)and LVEDV increased 15 ml/m2 (P<0.01), CO and CI increased 2.011/min and 1.231/(min m2), respectively,P<0.01. But LV pumping function changed slightly after DIL administration, LVEF and LVEDV increased only 0.03 and 5 ml/m2, respectively, P>0.05. In the group of patients with old myocardial infarction, both negative effect were observed.
出处
《核技术》
CAS
CSCD
北大核心
1990年第11期641-644,共4页
Nuclear Techniques
关键词
放射性
核素
心室
造影
阻滞剂
Radionuclide ventriculography Calcium-channel blocker LV function
