摘要
目的:探讨食管癌颈淋巴结转移放射治疗加局部热疗的临床疗效和方法。方法:回顾性分析248例食管癌颈淋巴结(306个受损病灶)患者,左颈87例,右颈143例,双颈11例,气管前7例。转移灶≤3cm 202个,3.1cm-5cm 18个,>5cm 18个。加热采用915MHz、2450MHz微波热疗机,温度控制在41℃-43℃,每周2次,每次45分钟。放射治疗6MV-X直线加速器或钴60治疗机,2Gy/次,5次/周,照射剂量50Gy-75Gy。结果:瘤体完全消失率为70.26%(215/306),部分消退16.01%(49/306),总有效率86.27%(264/306),稳定和无效13.73%(42/306)。结论:食管癌颈淋巴结转移加热和放疗综合应用是一种有效、易于进行、经济的姑息性治疗方法,可以提高肿瘤的局控率和治愈率。
Objective： To evaluate the efficiency of thermo-radiotherapy for esophageal carcinoma with neck metastasis, Methods： A retrospective analysis was performed on 248 patients with esophageal carcinoma and neck metastasis , The location of metastasis in left-neck, right- neck bilateral neck and pre-branch were 87,143, 11 and 7cases respectively, Using 915MHz,245MHz microwave to perfom therapy, Temperature was controlled in 41℃ - 43℃ ,45minutse per time, twice a week. Radiotherapy was performed with 6mv -x or ^60Co DT50 -70Gy,2Gy per fraction ,five times per week. Results. The CR,PR rates were 70, 26% （215/306） 16.01% （49/306）, The overall efficiency rate was 86.27% （264/306）, Conclusion： It is a effective way for esophageal carcinoma with neck metastasis by thermo-radiotherapy, and may improve local control rate.
出处
《现代肿瘤医学》
CAS
2008年第6期977-978,共2页
Journal of Modern Oncology
关键词
食管癌
颈淋巴结
微波热疗
放射治疗
esophageal carcinoma
neck lymph node metastasis
Microwave - hyperthermia
radiotherapy
