摘要
目的评价气囊扩张治疗贲门失弛缓症的疗效,并探讨术前患者下食管括约肌静息压可否作为气囊扩张治疗压力选择的依据.方法45例贲门失弛缓症患者,17例为对照组,28例为研究组.研究组中再根据术前下食管括约肌压力分为两组,压力大于20 mmHg为一组(20例),小于、等于20 mmHg为一组(8例).所有病例均在胃镜直视下行气囊扩张术,测定治疗前、治疗后3 d的下食管括约肌静息压、下食管括约肌松弛率,进行对比分析;并且随访半年,观察症状积分.结果研究组和对照组全部45例患者经扩张治疗后临床症状明显缓解,症状评分由(5.1±0.6)降至(1.3±0.6)(P<0.05).其中研究组中的2组患者从症状评分和术后3 d LESP、LESR的组间比较分析,气囊扩张治疗有效,且近期疗效无明显差异.结论气囊扩张治疗贲门失弛缓症的近期疗效肯定,术前下食管括约肌压力的高低可作为扩张治疗时气囊压力的选择指标.
Obiective To Evaluate the curative effect of pneumatic balloon dilatation in patients with achalasia. And study if the lower esophageal sphincter pressure （LESP） as the selected norm of dilation＇s pressure. Methods 45 patients were selected in this study. 17 cases in control group, 28 cases in study group. According to the LESP before dilation, the study group were separated into two small groups again. One group LESP 〉 20 mmHg, 20 cases, another LESP ≤ 20 mmHg, 8 cases. All patients were done the dilatation under gastroscope, and followed up for six months, asked for their clinical symptomes. Before and after dilation, both within 3 days, all patients were done the esophagus manometry, we analysed the LESP and lower esophagus sphincter relaxation rate （LESR） among the groups. Results In all patients the clinical symptom was obviously releaved. Symptom score from 5.1 ± 0.6 reduced to 1.3 ±0.6 （P 〈 0.05）. Analysising the symptom score and LESP, LESR of the two small group, we found that pneumatic balloon dilation had good curative effect in near future and had not obviously difference between the groups. Gonclusions Pneumatic balloon dilatation to treatment cardia achalasia has good curative effect in near future. The LESP before dilation would be the selected norm of dilatation＇ s pressure.
出处
《昆明医学院学报》
2008年第2期152-155,共4页
Journal of Kunming Medical College
关键词
贲门失弛缓症
下食管括约肌压力
下食管括约肌松弛率
气囊扩张治疗
Cardia Achalasia
Lower esophageal sphincter pressur
Pneumatic balloon dilation
Llower esophagus sphincter relaxation rate
