摘要
目的探讨新辅助化疗在局部晚期乳腺癌治疗中的应用价值.方法对73例局部晚期乳腺癌患者采用TEC方案,75 mg/m2、ivp、d1;EADM60 mg/m2、iv、d1;CTX 600 mg/m2、iv、d1;每3周1个疗程,共2～4个疗程.结果新辅助化疗后73例中,临床完全缓解(CR)16例,部分缓解(PR)48例,稳定(SD)9例,总有效(CR+PR)率87.67%.结论新辅助化疗在局部晚期乳腺癌治疗中有重要作用,TEC方案有较高缓解率.
Objective To evaluate the effect of the neoadjuvant chemotherapy in the treatment of locally advanced breast cancer. Methods 73 patient with locally advanced breast cancer were treated with TEC program, docetaxel 75 mg/m^2, ivp, dl; EADM 60 mg/m^2, iv, dl; CTX 600 mg/m^2, iv, dl; per day was carried out in a course of 3 week, and 2 - 4 courses were administered in all the patients preoperatively. Results After preoperative chemotherapy with primary lesions, there was complete response （CR） 16 case, Partial response （PR） 48 case, 9 case Stable disease （SD）. The overall response rate was 87.67%. Conclusions Neoadjuvant plays an important role in treatment of locally advanced breast cancer. TEC program has a high response rate.
出处
《昆明医学院学报》
2008年第2期148-151,共4页
Journal of Kunming Medical College
关键词
局部晚期乳腺癌
新辅助化疗
多西他赛
Locally advanced breast cancer
Neoadjuvant chemotherapy
Docetaxel
