摘要
目的:探讨补肾活血中药对慢性肾功能衰竭的治疗效果。方法:将40例慢性肾功能衰竭患者随机分为保元强肾Ⅱ号组及肾安加开搏通组治疗,观察其对血浆及尿SOD、MDA及肾功能影响。结果:两组治前均有血浆SOD降低及MDA增高(P<0.01),尿SOD及MDA均呈现增高(P<0.01),治疗组治后血浆SOD增高、MDA降低,尿SOD及MDA均降低(P均<0.01),BUN、SCr及CCr显著改善(P<0.01)。结论:保元强肾Ⅱ号片有增强抗氧化能力,抑制脂质过氧化作用,从而改善肾功能。
To observe the effect of Chinese herbs of replenishing Kidney in treating chronic renal failure(CRF).Methods:Forty patients with CRF wrer randomly divided into two groups,Baoyuan Qiangshen(BQ)Ⅱtablet group and essential amino acid added capoten group.The changes of plasma and urine superoxide dismutase(SOD)and malondialdehyde(MDA)and the kidney function indices were investigated before and after treatment.Results:Before treatment,SOD reduced and MDA of both groups increased(P<0.01),while urine SOD and MDA increased(P<0.01).After treatment,plasma SOD increased but MDA was reduced and urine SOD,MDA were also reduced(P<0.01).Although the BUN and serum creatinine reduced significantly,creatinine clearance rate elevated significantly(P<0.01).Conclusions:The BQⅡtablet could strengthen antioxidation and inhibit lipid peroxidation,so it was effective to improve kidney function.
作者
朱辟疆
周逊
韦先进
ZHU Pi-jiang;ZHOU Xun;WEI Xian-jin(Jiangsu Research Centre of Nephrolo-gy with TCM-WM,Jiangsu(212002))
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1997年第11期649-652,共4页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
肾功能衰竭
丙二醛
保元强肾Ⅱ号片
SOD
chronic renal failure
superoxide dismutase
malondialdehyde
Baoyuan QiangshenⅡtablet
