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TAO-G检测在多种良恶性疾病诊断中的应用

TAO G ASSAY USED IN DIAGNOSIS OF VARIOUS BENIGN DISEASES AND MALIGNANT TUMORS
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摘要 对急慢性肝炎、原发性肝癌、胃癌、结直肠癌患者血清用ELISA法检测TAO-G。结果:TAO-G对急慢性肝炎的检测结果与正常人无显著性差异,P>0.05;恶性肿瘤的检测结果与正常人比较差异非常显著,P<0.01;对原发性肝癌、胃癌、结直肠癌的阳性率分别是68.4%、71.0%、62.5%,胃癌的阳性诊断率较高。TAO-G与AFP、CEA、CA-50标志物联合应用,综合阳性率均较单项检测阳性率明显提高,统计处理联合检测两者间相关显著(P<0.01)。提示:TAO-G的检测对消化系统肿瘤的早期诊断、鉴别诊断、避免单项检测出现的漏诊有重要的临床意义。 The serum TAO G was assaied with ELISA in patients with acute and chronic hepatitis,stomach cancer,primary hepatocarcinoma and colon or rectum cancer.Result:The value of TAO G from the patients with acute and chronic hepatitis was not much higher than normal value( P >0.05).The value of TAO G from the patients with primary hepatocarcinoma,stomach cancer,colon and rectum cancer was much higher than normal value ( P <0.01).The positive reaction rate of TAO G ELISA was 68.4%,71.0% and 62.5% respectively.The combined positive reaction rate of tumor markers was much higher than the positive reaction rate with single measurement.The statistic analysis showed that there was a significant correlation between the positive reaction rate of TAO G and other tumor marker assays( P <0.01).Prompt:TAO G assay and combined assay with other tumor markers may be useful in the diagnosis of malignant tumors.
作者 薛磊 张积仁
出处 《免疫学杂志》 CAS CSCD 北大核心 1997年第4期252-253,共2页 Immunological Journal
关键词 TAO-G 肝炎 消化道肿瘤 ELISA 诊断 TAO G,AFP,CEA,CA 50,Tumor
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