摘要
回顾性分析高剂量率（HDR）和低剂量率（LDR）腔内后装治疗宫颈癌。LDR组采用我院1979年6月～1984年12月137铯腔内后装放射治疗子宫颈癌862例。HDR组采用我院1986年12月至1987年7月137铯腔内后装治疗宫颈癌135例。结果：5年存活率HDR组低於LDR组；Ⅱ级放射性直肠炎HDR组为13．0％，低於LDR组22．6％（P＜0．01）。两组Ⅱ、Ⅲ期患者中无癌存活5年以上者宫旁A点吸收剂量比值（HDR／LDR）为0．53～0．54。结论：此剂量率转换系数对指导临床实践有参考价值。
The authors present a retrospective study comparing low dose rate (LDR ) versus high dose rate (HDR ) 137 Cs Intracavitary afterloading brachytherapy in the treatment of carcinoma of uterine cervlx. In 862 patlents of the LDR group with carcinoma of uterlne cervix 137Cs intracavitary afterloading irradiation was given from June 1979 to December 1984 in our hospital. in the HDR group, 135 patients received the same treatment regime from December 1986 to July 1987. Five-year survival rate of the HDR group was lower than that of the LDR group. The incidence of grade 2 rectal complication was significantly less in HDR than in the LDR group (13. 0%: 22. 6% P<0. 01). The total dose to point A in HDR group for stage 2~3 tumor was reduced with an average HDR/LDR ratio of 0. 53~0. 54. This factor might be beneficial in clinical practice.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1997年第12期920-922,共3页
Chinese Journal of Clinical Oncology
关键词
放射治疗
剂量率
子宫肿瘤
铯
Uterine cervix carcinoma Dose rate Intracavitary afterloading irradiation
