期刊文献+

布-加综合征135例临床回顾性分析

Retrospective Analysis of Budd-Chiari Syndrome in 135 Patients
原文传递
导出
摘要 对2004年8月至2007年2月复旦大学附属中山医院收治的135例布-力口综合征患者进行回顾性分析。结果示135例患者中继发于恶性肿瘤105例(77.8%),无确切继发病因者29例(21.5%);其临床表现以黄疸(69.6%)、腹水(48.2%)、腹胀(40.7%)、下肢水肿(37.O%)为多见;可出现胆红素升高、凝血酶原时间延长、血清γ-谷氨酰转移酶升高;非创伤性辅助检查中可选择彩色多普勒血管超声、CT和MRI,阳性率分别为59.5%、69.5%、81.5%;血管造影术是诊断布-力口综合征的金标准;治疗方法以经皮血管内支架植入和(或)球囊扩张术为主,辅以溶栓、抗凝、抗血小板聚集和保肝、支持等内科治疗。提示布-力口综合征是一种临床综合征,但由于发病原因复杂、临床表现多样、实验室检查缺乏特异性,临床诊断难度增加。而血管造影术和支架植入治疗是行之有效的诊治方法。 A total of 135 patients diagnosed with Budd-Chiari syndrome (BCS)during August 2004 and February 2007 were reviewed and analyzed retrospectively. The results showed that 105 subjects (77.8%) caused by malignances, while 29 participants (21.5%) had no definite pathogens. The most commonly seen symptom included jaundice (69.6%), followed by ascites (48.2%), abdominal distention (40.7%) and lower extremity edema (37.0%). Higher levels of STB, PT and γ-GT were determined. Color Dopple ultrasound, CT and MRI could be helpful in diagnosing BCS; angiography remained the most accurate measurement. Main treatment strategies were stent implantation and/or balloon dilation. BCS is a clinical syndrome with no typical symptoms, which makes its management very difficult. A complete understanding of the condition will help reduce misdiagnosis. Angiography and stent implantation are primary ways to diagnose or treat BCS.
出处 《中华全科医师杂志》 2008年第5期333-335,共3页 Chinese Journal of General Practitioners
关键词 肝静脉血栓形成 诊断 治疗 Hepatic vein thrombosis Diagnosis Treatment
  • 相关文献

参考文献3

二级参考文献47

  • 1[1]Valla DC.The diagnosis and management of the Budd-Chiari syndrome:consensus and controversies.Hepatology 2003; 38:793-803
  • 2[2]Okuda K.Inferior vena cava thrombosis at its hepatic portion (obliterative hepatocavopathy).Semin Liver Dis 2002; 22:15-26
  • 3[3]Denninger MH,Chait Y,Casadevall N,Hillaire S,Guillin MC,Bezeaud A,Erlinger S,Briere J,Valla D.Cause of portal or hepatic venous thrombosis in adults:the role of multiple concurrent factors.Hepatology 2000; 31:587-591
  • 4[4]Janssen HL,Meinardi JR,Vleggaar FP,van Uum SH,Haagsma EB,van Der Meer FJ,van Hattum J,Chamuleau RA,Adang RP,Vandenbroucke JP,van Hoek B,Rosendaal FR.Factor V Leiden mutation,prothrombin gene mutation,and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis:results of a casecontrol study.Blood 2000; 96:2364-2368
  • 5[5]Hirshberg B,Shouval D,Fibach E,Friedman G,Ben-Yehuda D.Flow cytometric analysis of autonomous growth of erythroid precursors in liquid culture detects occult polycythemia vera in the Budd-Chiari syndrome.J Hepatol 2000; 32:574-578
  • 6[6]Anger BR,Seifried E,Scheppach J,Heimpel H.Budd-Chiari syndrome and thrombosis of other abdominal vessels in the chronic myeloproliferative diseases.Klin Wochenschr 1989; 67:818-825
  • 7[7]Valla D,Casadevall N,Lacombe C,Varet B,Goldwasser E,Franco D,Maillard JN,Pariente EA,Leporrier M,Rueff B.Primary myeloproliferative disorder and hepatic vein thrombosis.A prospective study of erythroid colony formation in vitro in 20 patients with Budd-Chiari syndrome.Ann Intern Med 1985; 103:329-334
  • 8[8]Pagliuca A,Mufti GJ,Janossa-Tahernia M,Eridani S,Westwood NB,Thumpston J,Sawyer B,Sturgess R,Williams R.In vitro colony culture and chromosomal studies in hepatic and portal vein thrombosis--possible evidence of an occult myeloproliferative state.Q J Med 1990; 76:981-989
  • 9[9]Wanless IR,Peterson P,Das A,Boitnott JK,Moore GW,Bernier V.Hepatic vascular disease and portal hypertension in polycythemia vera and agnogenic myeloid metaplasia:a clinicopathological study of 145 patients examined at autopsy.Hepatology 1990; 12:1166-1174
  • 10[10]Janssen HL,Meinardi JR,Vleggaar FP,van Uum SH,Haagsma EB,van Der Meer FJ,van Hattum J,Chamuleau RA,Adang RP,Vandenbroucke JP,van Hoek B,Rosendaal FR.Factor V Leiden mutation,prothrombin gene mutation,and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis:results of a casecontrol study.Blood 2000; 96:2364-2368

共引文献193

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部