摘要
目的研究显微镜下多血管炎（MPA）肺部受累的病理基础与影像学、临床表现特点。方法对2003-2006年收治的6例MPA患者的临床资料进行回顾性分析。结果肺部受累影像学表现：（1）两肺多发斑片状影3例。（2）两肺磨玻璃样密度影1例。（3）弥漫性肺间质改变2例。临床表现：肺部症状除咳嗽、咯痰外，多以咯血为主，肺外受累以肾功能损害为主。实验室检测6例患者抗中性粒细胞胞质抗体（ANCA）均阳性，5例为P-ANCA／MPO-ANCA阳性。结论MPA肺部受累CT影像学表现无明显特异性，结合临床及实验室检查，可以提高认识，早期诊治。
Objective To investigate the pathologic foundation, clinical characteristics and CT features of microscopic polyangiitis （MPA） with lung involvement. Methods Clinical data of 6 patients of MPA with lung involvement in 2003-2006 were retrospectively analyzed. Results The types of lung imaging manifestations as the followings： （ 1 ）Mutiple flaky shadow in both lung in 3 cases. （2） Ground-glass shadow in 1 ease. （3） Disseminated interslitial lung involvement in 2 cases. The main respiratory symptom was haemoptysis except cough and expectoration. Renal damaging often occurred besides the lung. Six eases with positive antineutrophil cytoplasmic antibody （ ANCA ） and 5 eases with positive P-ANCA/MPO-ANCA were found in laboratory examination. Conclusions The CT manifestations of MPA with lung involvement have no characteristic features. Clinical characteristics and laboratory examination can help to understand and diagnose MPA with lung involvement early.
出处
《中国医师进修杂志（内科版）》
2008年第5期18-20,共3页
Chinese Journal of Postgraduates of Medicine
