摘要
目的阐述姜黄素及其衍生物的最新研究进展。方法根据关于姜黄素及其衍生物的研究开发现状的多篇相关文献,对姜黄素的苯环和中间连接链的结构改造特点进行整理和归纳。结果与结论大多数姜黄素衍生物的生物活性都有所提高。另外还总结了一部分化合物的构效关系。
Objective To review the recent developments in the research of curcumin and its derivatives.Methods The structure modifications on benzene ring and the coupling chain of the curcumin were summarized on the basis of published literatures for curcumin.Results and conclusions Most compounds had better activities than curcumin.Moreover,the structure activity relationships of some compounds are summarized in the paper.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2008年第4期331-336,共6页
Journal of Shenyang Pharmaceutical University
关键词
姜黄素衍生物
抗氧化
抗癌
抗菌
curcumin derivatives
antioxidation
antitumor
antibacterial