摘要
目的:探讨曲唑酮对激越性抑郁症的疗效。方法:将入组病人随机分为2组,各40例,分别应用曲唑酮和阿米替林治疗,疗程4周,用汉密尔顿抑郁量表(HAMD)和副反应量表(TESS)评定疗效和副反应情况。结果:治疗4周后,2组对激越性抑郁均有良好疗效。曲唑酮与阿米替林疗效近似,两组相比,差异无显著性(P>0.05);但曲唑酮副反应小,程度交轻,两组相比,差异显著(P<0.05或P<0.01)。结论:曲唑酮治疗激越性抑郁安全,疗效确切。
Objective： To explore the efficacy of trazodone in the treatment of agitated clepression. Methods： 80 agitated depression patients meeting entrance condition were randomly divided into two groups.The 40 of total patients were treated with trazodone and the others were treated with amitriptylin for 4 weeks ,The therapeutic response and side effects were evaluated with the HAMD and TESS. Results：Trazodone and amitriptylin showed good effect in the treatment of agitated depression,trazodone had similar efficacy to amitriptylin and the comparison of the two groups showed no significant diffevence（P〉0.05）; But side effects of trazodone were less and milder, There was singnificant difference between the two groups（P〈0.05 or P〈0.01）. Conclusion：This study suggested that trazodone in a safe, reliable effect in the treatment of agitated depression.
出处
《中国伤残医学》
2008年第2期16-18,共3页
Chinese Journal of Trauma and Disability Medicine
