摘要
为预防和治疗肝癌经门静脉转移扩散,对42例无门静脉癌栓病人进行了预防性门静脉化疗,对18例已出现门静脉癌栓的病人进行了治疗性的门静脉化疗。所用化疗药为三联即表阿霉素30mg,丝裂霉素8mg,5-Fu500mg。结果门静脉穿刺化疗,在预防组门静脉癌栓发生率(19.04％)低于对照组(38.9％)(P值<0.05);在治疗组栓塞的门静脉部分或完全再通,肝癌门静脉癌栓消失率为11.1％,缩小率为61.1％,病人腹胀减轻,腹水减少,全身情况改善。本研究表明超声引导下经皮门静脉穿刺化疗,疗效确实,方法安全、简便、副作用小,无严重并发症发生。
In order to treat or prevent portal vein metastases of liver cancer, intraportal chemotherapies were carried on in 18 and in 42 patients with and without portal vein thrombosis. The agents used were Pharmorubicin 30 mg, Mitomycin—C 8 mg and 5—Flurouracil 500 mg. The results showed that the incidence of portal thrombosis in preventive group (19.04％) was lower than that in control group (38.9％) (P<0.05). Partial or complete reflow in portal vein with thrombosis was observed in treat group. The rates of disappearance and shrinkage of portal thrombosis were 11.1％ and 61.1％ respectively. Abdominal distention and ascites were reduced. The general condition was improved. It is suggested that ultrasound-guided percutaneous intraportal chemotherapy performance is effective, safe, convenient and has less side effects and no serious complication.
出处
《中华超声影像学杂志》
CSCD
1997年第6期295-298,共4页
Chinese Journal of Ultrasonography
关键词
肝肿瘤
门静脉
介入疗法
介入超声
药物疗法
liver neoplasm
portal vein
chemotherapy
interventional treatment
interventional ultrasound
