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变应性鼻炎发病机制研究进展 被引量:24

Research Progress on Etiopathogenesis of Allergic Rhinitis
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摘要 变应性鼻炎是外源性抗原引起的免疫性疾病,具有变应性素质的患者与超敏原初次接触后致使其处于致敏状态,当再次与该超敏原接触时,患者机体产生各种细胞、蛋白质及细胞因子参与或促进变应性鼻炎的发生、发展。目前,人们正从各个层面研究变应性鼻炎的病因及治疗,文章综述了变应性鼻炎的发病机制最新研究进展,对临床治疗具有指导意义。 Allergic rhinitis is an immunological disease, which is caused by exogenous antigens. The pa- tients with allergic predisposition will be at a sensitive state after the first contact with allergen. When they contact with the same allergen again, many cells, proteins and cytokines of the patients will help to accelerate the allergic rhinitis. Now,people are doing research on the etiopathogenesis and therapy from various perspectives. The article gives an overview about latest research development of etiopathogenesis of allergic rhinitis, which will give guidance for clinical therapy.
出处 《医学综述》 2008年第8期1205-1208,共4页 Medical Recapitulate
关键词 变应性鼻炎 细胞因子 趋化因子 趋化因子受体 Allergic rhinitis Cytokine Chemokine Chemokine receptors
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