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微量间接血球凝集试验检测血清中髓磷脂碱性蛋白抗体

Detection of Antibody to Myelin Basic Protein in Serum by Micromethod of Indirect Hemagglutination
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摘要 微量间接血球凝集试验检测血清中MBPA,方法简便,重复性较好。在MS(44例)、OND(35例)和正常人(36例)中,血清中MBPA异常增高的阳性率分别为70%、23%和11%。 This paper reports on influences of various factors on the micromethod of indirect hemagglutination during detection of MBPA in serum to choose the optimum experimental condition. Meanwhile, the levels of MBPA in serum of 44 MS, 35 OND patients and 36 normal people were detected bY this method. The results showed that it is simple, convenient and well reProducible. The abnormally increased rates of MBPA in serum were 70% for MS patients, 23% for OND and 11% for normal control. This showed that pathogenesis of MS might be related to formation of antibody to CNS.
出处 《哈尔滨医科大学学报》 CAS 1990年第4期285-288,共4页 Journal of Harbin Medical University
关键词 多发性硬化 MBPA 血球凝集试验 Multiple sclerosis Myelin basic protein antibody Hemagglutination
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