摘要
目的探讨与表浅性膀胱移行细胞癌复发、进展、生存相关的显著性因素。方法应用Cox风险比例模型和Kaplan-Meier法及Log-rank检验方法对153例表浅性膀胱移行细胞癌的13项指标与复发、进展及生存时间进行统计分析。结果发现与复发相关的因素为肿瘤的大小、组织学分级及膀胱灌注情况。影响进展的主要因素为肿瘤的形态、组织学分级、膀胱灌注情况及症状的持续时间。影响肿瘤特异生存率的变量为肿瘤的形态、组织学分级及症状的持续时间。结论对随访资料进行生存分析,组织学分级是影响预后的主要因素,膀胱灌注治疗是重要的保护性因素。
Objective To evaluate the prognosth, factors affecting recurrence,progression and cancer-specific survival in patients with prilnary superficial transitional cell carcinoma of bladder. Methods Using Kaplan-Meier method, Log-rank test and Cox proportional hazards model, the retrospective survival analysis was performed in 153 patients with superficial transitional cell carcinoma of bladder. Results The main variables affecting recurrence were tumor size, histological grades and intravesical chemotherapeutic instillations. The main variables affecting progression were tumor shape, histological grades,the duration of symptoms and intravesical chemotherapeutie instillations. The variables that could predict cancer specific survival were tumor shape, histological grades and the duration of symptoms. Conclusions By cancer-specific survival analysis of the follow-up data,we can identity the main prognostic factors was histological grades,intravcsical chemotherapeutic instillations was the protective tacter.
出处
《潍坊医学院学报》
2008年第1期79-81,共3页
Acta Academiae Medicinae Weifang
关键词
膀胱肿瘤
预后
移行细胞
Bladder tumor
Prognosis
Transitional cell
