摘要
[目的]探讨血液灌流加血液透析的方法和疗效,分析急性中毒患者血清TNF-α及IL-6含量与治疗和预后相关性。[方法]抽取急性中毒患者治疗前后静脉血,血清TNF-α及IL-6含量检测采用放免测定方法,血液灌流加血液透析治疗急性药物、毒物中毒患者30例,比较患者治疗前后血清中TNF-α、IL-6含量。[结果]30例中,痊愈27例(90.0%),死亡3例;患者治疗前后血清中TNF-α、IL-6含量高低有显著性差异(P<0.01),且其含量愈高,则死亡率愈高。[结论]血清中TNF-α、IL-6参与其发病和病理过程,治疗效果及预后与之相关;血液灌流加血液透析是急性重症中毒抢救的最佳选择方案之一。
[Objective] To explore the method and effect of blood perfusion and dialysis,and analyse the relativity between treatment and prognosis of acute toxic patients with their serum TNF-α and IL-6. [Method] Draw such patients＇ vein blood before and after treatment,make content test with radio-immune method to the serum TNF-α and IL-6 ;administer blood perfusion and dialysis to 30 cases of acute medicinal toxic patients,compare their TNF-α and IL-6 contents before and after treatment. [Result] 27 cases（90.0%） were cured, 3 dead; their TNF-α and IL-6 contents had marked difference between before and after treatment（P〈 0.01） ,more content, more death rate. [Conclusion] TNF-α and IL-6 contents are related with disease attack and pathological course,cure effect and prognosis;blood perfusion and dialysis is one of best plans for rescuing acute severe toxic patients.
出处
《浙江中医药大学学报》
CAS
2008年第2期181-182,共2页
Journal of Zhejiang Chinese Medical University
