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白血病多药耐药形成的分子机制研究进展 被引量：2

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作者 季丽娟 黄建鸣 李戈
机构地区 四川省人民医院儿科 四川省肿瘤医院肿瘤研究所
出处 《四川医学》 CAS 2008年第4期464-466,共3页 Sichuan Medical Journal
基金 四川省科技厅基金资助(项目编号05JY029-039)
关键词 白血病 多药耐药 环氧化酶-2 分子机制
分类号 R733.7 [医药卫生—肿瘤]
  • 相关文献

参考文献16

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  • 2Plasschaert SL, Vellenga E,de Bont ES, et al. High functional P-glycoprorein activity is more often present in T-cell acute lymphoblastic leukaemic cells in adults than in children[J]. Leuk Lymphoma,2003,44( 1 ) :85 - 95
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  • 4Van der Kolk DM, de Vries EG, Noordhoek L, et al. Activity and expression of the multidrug resistance proteins P-glycoprotein, MRPI, MRP2, MRP3 and MRP5 in denovo and relapsed acute myeloid leukemia[ J]. Leukemia, 2001,15(10) : 1544 - 1553
  • 5Plasschaert SL, de Bont ES, Boezen M, et al. Expression of muhidrug resistance-associated proteins predicts prognosis in childhood and adult acute lymphoblastic leukemia[ J]. Clin Cancer Res, 2005, 11 (24 Pt1 ) : 8661 - 8668
  • 6Valera ET, Scrideli CA, Queiroz Rg, et al. Multiple drug resistance protein ( MDR-1 ), multidrug resistance-related protein (MRP) and lung resistance protein(LRP) gene expression in childhood acute lymphoblastic leukemia [J] .Sao Paulo Med J,2004,122(4) : 166 - 177
  • 7Huh H J, Park CJ,Jang S, et al. Prognostic significance of multidrug resistance gene 1 (MDR1), multidrug resistance-related protein(MRP) and lung resistance protein(LRP)mRNA expression in acute leukemia[J]. J Korean Med Sci,2006,21(2) :253 - 258
  • 8Van den Heuvel Eibrink MM,Wiemer EA, Prins A, et al. Increased expression of the hreast cancer resistance protein(BCRP)in relapsed or refractory acute myeloid leukemia (AML) [ J ]. Leukemia, 2002, 16 ( 5 ) : 833 - 839
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同被引文献27

  • 1何莉,侯克佐.bcl-2,MDR1基因及编码蛋白在儿童急性白血病骨髓单个核细胞中表达的研究[J].中国医科大学学报,2004,33(5):463-465. 被引量：1
  • 2刘筱梅,徐酉华,于洁,邓兵,苏庸春.儿童急性白血病survivin,bcl-2,mdr1的表达及意义[J].重庆医科大学学报,2006,31(2):215-218. 被引量：6
  • 3张伟,张丽达,汪爱国,黄培林.高压氧对结肠癌LoVo细胞周期的影响[J].中华航海医学与高气压医学杂志,2006,13(2):88-91. 被引量：8
  • 4王丹,克晓燕,胡永芳.MDR1基因多态性及表达与急性白血病患者预后相关性的研究进展[J].中国药理学通报,2007,23(6):707-710. 被引量：3
  • 5Efferth T, Sauerbrey A, Steinbach D, et al. Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia [J]. Int JOncol, 2003, 23(2): 509-517.
  • 6Plasschaert SL, Groninger E, Boezen M, etal. Influence of ftmctional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic leukemia [J]. Clin Pharmacol Ther, 2004, 76(3): 220-229.
  • 7Hattori H, Suminoe A, Wada M, et al. Regulatory polymor- phisms of multidrug resistance 1 (MDR1) gene are associated with the development of childhood acute lymphoblastic leuke- mia[J].LeukRes, 2007, 31(12): 1633-1640.
  • 8Jamroziak K, Mynarski W, Balcerczak E, et al. Functional C3435T polymorphism ofMDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lympho- blastic leukemia [J]. EurJHaematol, 2004, 72(5): 314-321.
  • 9Leal-Ugarte E, Guti6rrez-Angulo M, Macias-G6mez NM, et al. MDRI C3435T polymorphism in Mexican children with acute lymphoblastic leukemia and in healthy individuals [J]. HumBiol, 2008, 80(4): 449-455.
  • 10Rao DN, Anuradha C, Vishnupriya S, et al. Association of anMDR1 gene (C3435T) polymorphism with acute leukemia in India[J].AsianPacJCancerPrev, 2010, 11(4): 1063-1066.

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二级引证文献1

四川医学
2008年 第4期

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