摘要
目的探讨早期鼻肠管肠内营养在减轻急性重症胰腺炎（ASP）急性炎症反应和改善疾病转归中的作用。方法对2000年6月至2006年6月78例ASP前瞻性的随机分成两组，38例接受全肠外营养（TPN）组成TPN组，40例早期鼻肠管肠内营养，组成EN组，检测78例ASP病人APACHEⅡ评分、C反应蛋白、血清白蛋白指标，按随机接受肠内、肠外营养7d后再检测上述指标；同时观察MOF的发生率、胰周脓肿感染率、外科手术干预率。结果肠内营养组7d后急性炎症反应指标：C反应蛋白、APACHEⅡ明显改善（P〈0．05），TPN组上述指标无明显改变；MOF的发生率、胰周脓肿感染率、外科手术干预率，肠内营养组明显降低（P〈0．05）。结论早期鼻肠管肠内营养可缓和急性重症胰腺炎病人的急性炎症反应；明显减少MOF的发生率、胰周脓肿感染率、外科手术干预率，能改善疾病的愈后，SAP病人，血液流动学稳定，肠功能基本恢复时营养支持优先考虑鼻肠管肠内营养。
Objective To investigate the role of the early use of bengmark tube eternal nutrition in the treatment of acute severe pancreatitis（ASP）. Methods A total of 78 patients with ASP were randomized into 2 groups, one group received parenternal nutrition （PN group） and the other eternal nutrition （EN group）. We evaluated APACHE Ⅱ score, C reactive protein （CRP）, and endotoxin （albumin） on the 1st and 7tb d after treatment. Results Systemic inflammatory response syndrome （SIRS）, multiple organ failure, infection around pancreas and surgical intervention ratio were signifi- candy decreased in the EN group. The SIRS at the acute stage was markedly decreased and the prognosis was better in the EN group. CRP： 157±31.39 to 83±26.34, P〈0.05. APACHEⅡ scores： 11.87±4.67 to 7.85±1.36, P〈0.05. Conclusion The early use of bengmark tube EN can decrease the SIRS in the acute phase of ASP and improve clinical prognosis of ASP. It is clinically beneficial.
出处
《中华肝胆外科杂志》
CAS
CSCD
2008年第3期149-151,共3页
Chinese Journal of Hepatobiliary Surgery
关键词
胰腺炎
肠内营养
肠外营养
Pancreatitis
Enteral nutrition
Parenteral nutrition
