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重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白致狼疮样综合征一例 被引量：3

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摘要 随着重组人Ⅱ型肿瘤坏死因子（TNF）受体-抗体融合蛋白（益赛普）使用的不断增加，诸多不良反应相继被发现，但致狼疮样综合征的报道较少，本文报告1例，以期引起临床医师的关注。
作者 王春燕 王轶 王丽萍
机构地区 兰州大学第二医院风湿科
出处 《中华风湿病学杂志》 CAS CSCD 2008年第4期288-288,共1页 Chinese Journal of Rheumatology
关键词 肿瘤坏死因子受体 狼疮样综合征 抗体融合蛋白 人Ⅱ型 重组 不良反应 临床医师
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献5

  • 1张亚美,李晓兰,赵岚,李超.强直性脊柱炎病人应用益赛普治疗局部反应的临床观察[J].护理研究（上旬版）,2006,20(3):610-612. 被引量：24
  • 2Valesini G, Mmontecucco C, Cutolo M. Recommendations for the use of biologic (TNF-alpha blocking) agents in the treatment of rheumatoid arthritis in Italy. Clin Exp Rheumatol, 2006, 24: 413- 423.
  • 3Mor A, Bingham C, Barisoni L, et al. Proliferative lupus nephritis and leukocytoclastic vasculitis during treatment with etanercept. Rheumatol, 2005, 32: 740-743.
  • 4Kang MJ, Lee YH, Lee J, et al. Etanercept-induced systemic lupus erythematosus in a patient with rheumatoid arthritis. Korean Med Sci, 2006, 21: 946-949.
  • 5Shakoor N, Michalska M, Harris CA, et al. Drug-induced systemic lupus erythematosus associated with etanercept therapy. Lancet, 2002, 359: 579-580.

二级参考文献6

  • 1Breedveld FC. Tumour necrosis factor antagonists: Infliximab, adalimumab and etanercepr [J]: Nededands Tijdschriftvoor Genecskunde, 2005, 149(41):2273-2277.
  • 2Clelland S, Hunek JR. Etanercept injection site reaction[J]. Dermatology Nursing, 2005,17(5):375.
  • 3Haraoui B, Differentiating the efficacy of tumor necrosis factor inhibitors [J]. Journal of Rheumatology Supplement, 2005,74:3-7.
  • 4Soliotis F, Glover M, Jawad AS. Severe skin reaction after leflunomide and etanercept in a patient with rheumatoid arthritis [J]. Annals of the Rheumatic Diseases,2002,61(9):850-851.
  • 5Rita Bunikowski, Kerstin Gerhold,Matthias Brautigem, et al. Effect of low-dose cyclosporin A microemulsionon disease severity, interleukin-6, imerleukin-8 nd tumor necrosis factor alpha production in severe pediatric atopic dermatitis [J]. Internationl Archives of Allergy and Immunology,2001,125(4):344-348.
  • 6Leonardo H Tonelli, Teodor T Postolache. Tumor necrosis factor alpha, interleukin-1 beta, interleukin-6 and major histocompatibility complex molecules in the normal brain and after peripheral immune challenge [J]. Neurlogical Research, 2005,27(7): 679-684.

共引文献23

同被引文献34

  • 1胡大伟,鲍春德,陈顺乐,古洁若,栗占国,孙凌云,韩星海,倪立青.重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白治疗类风湿关节炎双盲随机多中心对照临床研究[J].中华风湿病学杂志,2005,9(11):664-668. 被引量：86
  • 2郝慧琴,黄烽,唐捷,邓小虎,张亚美,索塔林,方显峰.不同剂量重组人Ⅱ型肿瘤坏死因子受体-Fc融合蛋白治疗强直性脊柱炎疗效比较[J].中华风湿病学杂志,2007,11(4):202-205. 被引量：17
  • 3Bathon JM,Martin RW,Fleischmann RM,et al.A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis.N Engl J Med,2000,343:1586-1593.
  • 4Klareskog L,van der Heijde D,de Jager JP,et al.Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis:double-blind randomised controlled trial.Lancet,2004,363:675-681.
  • 5Emery P,Breedveld FC,Hall S,et al.Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active,early,moderate to severe rheumatoid arthritis (COMET):a randomised,double-blind,parallel treatment trial.Lancet,2008,372:375-382.
  • 6Rudwaleit M,van der Heijde D,Landewé R,et al.The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part Ⅱ):validation and final selection.Ann Rheum Dis,2009,68:777-783.
  • 7Davis JC Jr,Van Der Heijde D,Braun j,et al.Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis:a randomized,controlled trial.Arthritis Rheum,2003,48:3230-3236.
  • 8Davis JC Jr,van der Heijde DM,Braun J,et al.Efficacy and safety of up to 192 weeks of etanercept therapy in patients with ankylosing spondylitis.Ann Rheum Dis,2008,67:346-352.
  • 9Dijkmans B,Emery P,Hakala M,et al.Etanercept in the longterm treatment of patients with ankylosing spondylitis.J Rheumatol,2009,36:1256-1264.
  • 10van der Heijde D,Da Silva JC,Dougados M,et al.Etanercept 50 mg once weekly is as effective as 25 mg twice weekly in patients with ankylosing spondylitis.Ann Rheum Dis,2006,65:1572-1577.

引证文献3

二级引证文献45

中华风湿病学杂志
2008年 第4期

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