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成人斯蒂尔病发病机制的研究进展 被引量：3

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摘要 幼年特发性关节炎全身型由George Still于1897年首次报道，故亦被称为斯蒂尔病（Still’s disease）。在成年期起病即称为成人斯蒂尔病（adult-onset Still’s disease，AOSD）。在疾病活动期铁蛋白^[1]、白细胞介素（IL）-18^[2]等血清标志物的异常升高对AOSD的诊断很有价值。目前诊断该病仍主要基于患者的临床表现和是否对激素治疗有反应。因此，对AOSD发病机制的深入研究有助于临床诊断与治疗。
作者 黄轩 赵东宝 戴生明
机构地区 第二军医大学附属长海医院风湿免疫科
出处 《中华风湿病学杂志》 CAS CSCD 2008年第4期269-271,共3页 Chinese Journal of Rheumatology
基金 国家自然科学基金资助项目（30672112） 全军医药卫生科研基金资助项目（06Q45） 上海市浦江人才计划资助项目（06PJ14121）
关键词 成人斯蒂尔病 病发病机制 幼年特发性关节炎 GEORGE 临床诊断 AOSD 激素治疗 血清标志物
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献25

  • 1连帆,杨岫岩,梁柳琴,叶玉津,詹钟平,许韩师.血清铁蛋白水平对成人斯蒂尔病诊断的临床价值[J].中华风湿病学杂志,2005,9(6):338-341. 被引量：52
  • 2Efthimiou P, Kontzias A, Ward CM, et al. Aduh-onset Still's disease: can recent advances in our understanding of its pathogenesis lead to targeted therapy? Nat Clin Pract Rheumatol, 2007, 3: 328-335.
  • 3戴生明,冷伟建,韩星海,沈茜.成人Still病患者血清细胞因子水平及与病情活动性的关系[J].第二军医大学学报,2002,23(12):1351-1356. 被引量：10
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二级参考文献25

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共引文献63

同被引文献21

  • 1刘毅,黄次波.成人斯蒂尔病诊断标准的探讨[J].中华内科杂志,1993,32(9):603-606. 被引量：28
  • 2杨岫岩.成人斯蒂尔病诊断与治疗[J].实用医院临床杂志,2007,4(3):15-16. 被引量：8
  • 3顾菲,孙凌云.成人斯蒂尔病研究进展[J].中华风湿病学杂志,2007,11(7):435-438. 被引量：6
  • 4Dudler J-Revaz S.Adult-onset Still's disease.Rev Med Suisse,2008,4(149):702,704-706.
  • 5Tabak F,Mert A,Celik AD,et al.Fever of unknown origin in Turkey.Infection,2003,31(6):417-420.
  • 6郑毅.成人斯蒂尔病//匡培根.神经系统疾病药物治疗学.2版.北京:人民卫生出版社,2008:1441-1446.
  • 7Eflhimiou P,Kontzias A,Ward CM,et al.Adult-onset Still's disease:can recent advances in our understanding of its pathogenesis lead to targeted therapy ?.Nat Clin Pract Rheumatol,2007,3(6):328-335.
  • 8Eflhimiour P,Georgy S.Pathogenesis and management of adult onset Still's disease.Semin Arthritis Rheum,2006,36(3):144-152.
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引证文献3

二级引证文献5

中华风湿病学杂志
2008年 第4期

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