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人滑膜间充质干细胞的研究现状 被引量:6

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摘要 间充质干细胞 (mesenchymal stem ceils, MSCs) 是指来源于间充质组织,具有高度增殖和多向分化潜能的克隆原细胞。近年来,随着组织细胞工程学和基因工程学的发展,利用MSCs的多项分化潜能,在组织工程、细胞因子替代治疗、基因治疗及再生医学等方面的应用研究已成为热点。越来越多的研究表明:MSCs除存在于骨髓组织外,还可从滑膜、骨膜、骨骼肌和脂肪组织等成人间充质组织中分离获得,而且不同来源的MSCs在体内发挥着不同的功能。2001年,DeBari等首先报告在成人滑膜组织中可以分离获得MSCs,即人滑膜MSCs。
作者 芮云峰 王友
出处 《中华关节外科杂志(电子版)》 CAS 2007年第1期60-62,共3页 Chinese Journal of Joint Surgery(Electronic Edition)
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参考文献4

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共引文献9

同被引文献105

  • 1宁红梅,金建刚,扈江伟,冯凯,陈虎.人骨髓间充质干细胞体外对异基因T淋巴细胞表型的影响[J].中国实验血液学杂志,2005,13(1):43-49. 被引量:23
  • 2邱林,金先庆,罗小辑,丁幸坡.转化生长因子β_3基因转染兔骨髓间充质干细胞的实验研究[J].中国修复重建外科杂志,2006,20(9):940-943. 被引量:6
  • 3张经纬,曾炳芳,赵金忠.碱性成纤维细胞生长因子转染对半月板纤维软骨细胞增殖、细胞周期及胶原合成影响的研究[J].中国修复重建外科杂志,2006,20(12):1253-1256. 被引量:6
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