摘要
靶向免疫疗法是白血病和淋巴瘤治疗中的一种重要手段和研究热点。这种疗法的关键步骤是先找到白血病和淋巴瘤发病机制中的主要或关键致病蛋白质或在肿瘤细胞膜上所表达的抗原(这种抗原较特异或在数量和频率上较高),然后针对这种靶点通过主动、被动或过继免疫疗法进行治疗。①主动免疫疗法是用靶点蛋白制备疫苗,如用独特型(Id)免疫球蛋白(Ig)、DNA、膜蛋白脂质体(MPL)、树突状细胞等制备疫苗。
出处
《内科理论与实践》
2008年第2期69-75,共7页
Journal of Internal Medicine Concepts & Practice
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