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第三次痰涂片检查在摩尔多瓦和乌干达结核病诊断中的有效性

Efficiency of a third serial sputum smear examination in the diagnosis of tuberculosis in Moldova and Uganda
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摘要 地点:摩尔多瓦和乌干达分别有24和30个结核病(TB)显微镜检查实验室。目的:评价第3次痰涂片检查对确诊1例增加的TB病例所需的工作量。方法:采用实验室登记回顾性研究,通过第3次痰涂片检查确定TB患病率和增加的病例数,TB病例来源于摩尔多瓦和乌干达的疑诊患者,这2个地区可以提供用于确诊1例增加的TB病例所需的检查数量。结果:在摩尔多瓦有9%(1141/12525),在乌干达有20%(7280/36054)的疑诊病例通过至少1次阳性痰涂片确诊为TB病例。通过第3次检查得到的增加病例比例在摩尔多瓦是4%,在乌干达为3%。为了通过第3次痰涂片检查而确诊1例增加的TB病例,在摩尔多瓦需检查273张涂片(95%可信区间200—389)、乌干达需检查175张涂片(95%可信区间153—222),平均确诊时间分别为11d(8～16)和7d(6～9)。结论:在这2个国家,第3次痰涂片检查对诊断痰涂片阳性TB是无效的。
作者 A. Katamba D. Laticevschi. H. L. Rieder 张宗德（译） 屠德华（校） 张立兴（审）
机构地区 Case Western Reserve University Tuberculosis/AIDS Project Coordination Unit International Union Against Tuberculosis and lung Disease 不详
出处 《国际结核病与肺部疾病杂志》 2007年第4期132-136,共5页 The International Journal of Tuberculosis and Lung Disease
基金 supported by the United States Agency for International Development under the terms of Award No. HRN-a-00-00-00018-00 supported by the International Clinical Operational and Health Services Research Program in TB and AIDS (TW-006900) in pursuance of obtaining a doctoral degree (PhD)
关键词 病例发现 增加的例数 显微镜 结核病 工作量
分类号 R52 [医药卫生—内科学]
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参考文献10

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国际结核病与肺部疾病杂志
2007年 第4期

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