摘要
目的:探讨不同剂量的三磷酸腺苷(ATP)对转复阵发性室上性心动过速(PSVT)的疗效。方法:将120例PVST患者随机分为4组,分别以不同剂量的ATP(第一组:0.1mg/kg,第二组:0.2mg/kg,第三组:0.3mg/kg,第四组:0.4mg/kg),快速静脉推注,未转复者,3分钟后重复同样剂量再给药1次,观察每组患者的转复时间、有效率、不良反应及转复时伴发的心律失常。结果:0.1mg/kg组的转复时间、有效率与其他3组比较有统计学差异(P<0.05)。0.4mg/kg组伴发严重缓慢心律失常较高。结论:以剂量为0.2～0.3mg/kg的ATP治疗PSVT是安全有效的,且严重心律失常发生率较低。
Objective：To investigate the influence of different doses of adenosine triphosphate （ATP） on the curative effect of converting paroxysmal supraventricular tachycardia （PSVT）.Methods：120 patients with PSVT were randomly divided into four groups,with different doses of ATP in each group （group 1 0.1 mg/kg,group 2 0.2 mg/kg,group 3 0.3 mg/kg,group 4 0.4 mg/kg）,the medicine in all groups was given by rapid intravenous injection.The same dose was injected once again 3 minutes later,if it did not work.The conversion time,the effective rate,the adverse reaction and the concomitant arrhythmia during the conversion in each were observed respecitvely. Results：There was statistical difference in the conversion time and effective rate between group 1 and other three groups（P〈0.05）.However,the serious concomitant arrhythmia in group 4 was higher than other three groups.Conclusion：The dose of ATP 0.2 mg/kg or 0.3 mg/ kg is safe and effective in the treatment of PSVT, and the incidence of serious arrhythmia is low.
出处
《现代医药卫生》
2008年第7期970-972,共3页
Journal of Modern Medicine & Health
关键词
阵发性室上性心动过速
三磷酸腺苷
剂量
Paroxysmal supraventrieular tachycardia
Adenosine triphoscphate
Dose
