摘要
目的：观察食管静脉曲张硬化治疗中应用善得定的情况。方法：将临床资料分为２组：治疗组３１例次，为硬化治疗过程中合并应用善得定，分别于术前３０ｍｉｎ及术后８ｈ皮下注射善得定１００μｇ；对照组４４４例次，为只作硬化治疗。２组其它治疗相同。观察术中出血、术后５ｄ内出血及输血量、术后１５ｄ内死亡率。结果：治疗组和对照组的术中每例出血分别为２１ｍｌ和８６ｍｌ（Ｐ＜００１），术后５ｄ内出血例次分别为１／３１和３８／４４４（Ｐ＞００５），５ｄ内平均输血量分别为３６６ｍｌ和７７４ｍｌ（Ｐ＜００５），术后１５ｄ内死亡人数分别为０和６人。结论：食管静脉曲张硬化治疗合并应用善得定，可使术中出血减少，术后５ｄ内输血量减少。
Objective:To observe bleeding during esophageal varices by sclerotherapy with octreotide.Methods:There were 152 patients,475 session,and divided into two groups:trial group of 15 parients,31 session,were assigned to receive two doses of octreotide 100 μg subcutaneously at 30 minutes before and 8 hours after sclerotherapy;control group of 137 cases,444 session,was assigned to receive sclerotherapy only.The bleeding during sclerotherapy,the quantity of blood transfusion within five days and mortality during 15 days after the treatments were observed.Results:Mean bleeding quantities were 21 ml(in trial group) and 86 ml(in control group) per session( P <0 01).There were 1/31 and 38/444 session( P >0 05) with bleeding and mean blood transfusion quantities were 336 ml and 774 ml( P <0 05),dead cases were zero and six for trial and control group,respectively.Conclusion:Esophageal varices sclerotherapy with octreotide resulted in reduced bleeding during the treatment and reduced blood transfusion quantity within 5 days after sclerotherapy.
出处
《中日友好医院学报》
1997年第3期202-204,共3页
Journal of China-Japan Friendship Hospital
