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白细胞介素-1结构与功能关系的研究进展 被引量:1

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摘要 白细胞介素-1(IL-1)是一种作用非常广泛的多肽生长因子,了解IL-1结构与功能的关系对阐明其作用机理是很有必要的。IL-1β含12条反向平行β折叠链,其三维结构象四面体,IL-1α的二级结构和高级结构与IL-1β相似;IL-1的一些子肽和氨基酸残基在IL-1与受体的结合和IL-1功能的发挥中起着重要作用。本文主要就IL-1的二级结构与三级结构,IL-1结构与功能关系的研究进展作一简要综述。
作者 郭甫坤
出处 《国外医学(分子生物学分册)》 CSCD 1997年第5期216-219,共4页
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