期刊文献+

液基细胞学和电子阴道镜在宫颈癌筛查中的效果 被引量:4

The Effect of Liquid-based Cytologic Test and Colposcopy in Cervical Cancer Screening
暂未订购
导出
摘要 [目的]评价我国河南省农村地区使用液基细胞学和阴道镜筛查宫颈癌的效果。[方法]对河南省新密市20~54岁农村女性开展以人群为基础的宫颈癌横断面调查。对妇女进行阴道镜检查,收集并分析宫颈脱落细胞标本和活组织标本检查结果。[结果]细胞学检测灵敏度为70.0%,特异度97.9%,阳性预测值28.0%,阴性预测值99.6%。阴道镜检测灵敏度为70.0%,特异度94.4%,阳性预测值12.5%,阴性预测值99.6%。细胞学和阴道镜检测的约登指数分别是67.9%和69.6%,粗一致率分别97.6%和94.1%。[结论]液基细胞学和阴道镜检查对于宫颈癌筛查灵敏度和特异度都较高。 [Purpose] To evaluate the screening effects of liquid-based cytologic test (LCT) and colposcopy for cervical cancer. [Methods] A population based cross-sectional study on women aged 20~54 with cervical cancer in Xinmi city,Henan province undergoing,colposcopy,cervical cytology and biopsy examination were analyzed. [Results] For LCT,the sensitivity,specificity,positive predictive value and negative predictive value were 70.0%,97.9%,28.0% and 99.6%,respectively. For colposcopy,the sensitivity,specificity,positive predictive value and negative predictive value were 70.0%,94.4%,12.5% and 99.6%,respectively. Youden's indexes for LCT and colposcopy were 67.9% and 64.4%,respectively. Crude agreement for LCT and colposcopy were 97.6% and 94.1%,respectively. [Conclusion] Both LCT and colposcopy have high sensitivity and high specificity for cervical cancer screening.
出处 《中国肿瘤》 CAS 2008年第3期179-181,共3页 China Cancer
关键词 宫颈肿瘤 液基细胞学 阴道镜 筛查 cervix neoplasms liguid-based cytologic test colposcopy screening
  • 相关文献

参考文献5

  • 1Parkin DM, Bray F, Ferlay J, et al. Global cancer statistics, 2002[J]. CA Cancer J Clin, 2005, 55(2):74-108.
  • 2李连弟,鲁凤珠,张思维,牧人,孙秀娣,皇甫小梅,孙杰,周有尚,欧阳宁慧,饶克勤,陈育德,孙爱明,薛志福,夏毅.中国恶性肿瘤死亡率20年变化趋势和近期预测分析[J].中华肿瘤杂志,1997,19(1):3-9. 被引量:868
  • 3Joseph MG, Cragg F, Wright VC, et al. Cyto-histological correlates in a colposcopic clinic: a 1-year prospective study[J]. Diagn Cytopathol, 1991, 7 (5) :477-481.
  • 4Kristensen GB, Skyggebjerg KD, Hφlund B, et al. Analysis of cervical smears obtained within three years of the diagnosis of invasive cervical cancer[J]. Acta Cytol, 1991, 35(1 ):47-50.
  • 5Benedet JL, Matisic JP, Bertrand MA. The quality of community colposcopic practice[J]. Obstet Gynecol, 2004, 103 (1):92-100.

共引文献867

同被引文献60

  • 1宫海霞,张新颖,隋丽丽,张艳芳.TCT筛查、阴道镜活检及病理在宫颈癌筛查中的应用[J].中外医疗,2008,27(27). 被引量:5
  • 2梅平,刘艳辉,庄恒国,曾仁海,张威,陈国艳,钱德英.1747例宫颈阴道病变筛查结果分析[J].临床与实验病理学杂志,2005,21(1):70-72. 被引量:31
  • 3李艳红,杨瑛,丁迎春,牟丽,张伟.液基细胞薄片以及阴道镜在宫颈癌及宫颈上皮内瘤变筛查中的应用[J].西南国防医药,2006,16(2):138-140. 被引量:2
  • 4欧小红.液基细胞学联合阴道镜检查对早期宫颈病变的诊断价值[J].中国民康医学,2006,18(14):490-491. 被引量:3
  • 5Wright TC Jr, Cox JT, Massad LS, Carlson J, Twiggs LB, Wilkinson EJ, American Society for Colposcopy and Cervical Pathology. 2001 consensus guidelines for the management of women with cervical intraepithelial neoplasia[ J ]. Am J Obstet Gynecol. 2003, 189(1):295-304.
  • 6Cuzick J. Overview of the European and North American studies on HPV testing in primary cervical cancer screening, Int J Cancer 2006, in press ( DOI : 10. 1002/ijc. 21955 ).
  • 7Cochand -Priollet B, Ziol M. Commission " frottis cervico - uterins" de l'AFAQAP, Cartier I, Dubois A, Michiels -Marzais D, Muller J, Picot R, Tartar MD, Vacher - Lavenu MC, and Vincent S. Progress report on the Bethesda System[ J]. Annales de pathologie ,2006,10( 5 ) :382.
  • 8Smith JS ,lindsay L, Keys J et al. HPV type distribution in invasive cervical cancer and high - grade cervical neoplasia : an update of recta - analyses and identification of global data gaps [ J ]. Int J Cancer,2007,121 ( 3 ) :621.
  • 9Clifford GM, Smith JS, Plummer Met al. Human papillomavirus types in invasive cervical cancer worldwide:a metaanalysis[J]. Br J Cancer ,2003,88( 1 ) :63.
  • 10American College of Obstretics and Gynecology Committee on Adolescent Health Care. Evaluation and management of abnormal cervical cytology and histology in the adolescent. Obstet Gynecol. 2006,4,107.

引证文献4

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部