摘要
目的观察不稳定型心绞痛(unstable angina pectoris,UAP)患者窦性心率震荡(heart rate turbulence,HRT)现象的特征并探讨其临床意义。方法选择62例UAP患者和在性别、年龄上相匹配的60例健康者分别作为UAP组和对照组,UAP组内分为高危组(n=20)、中危组(n=22)、低危组(n=20);均接受24 h Holter检查,定量测量HRT包括震荡初始(TO)和震荡斜率(TS)2个指标,并进行统计学处理。结果UAP组TO明显高于对照组〔(0.16±0.33)%vs.(-1.59±0.70)%,P<0.01〕,TS明显低于对照组〔(2.15±0.04)ms/RRI vs.(3.11±0.09)ms/RRI,P<0.05〕;UAP组中低危组TO明显低于高危组〔(-0.07±0.34)%vs.(0.18±0.15)%,P<0.01〕,低危组TS明显高于高危组〔(2.16±0.22)ms/RRI vs.(2.03±0.19)ms/RRI,P<0.05〕;中危组与高危组及低危组与中危组比较均无明显差异。结论UAP患者中HRT现象明显减弱,在高危组和低危组之间差异有显著性,可以作为预测UAP预后和高危患者的新指标。
Objective To explore the features of heart rate turbulence （HRT） in patients with unstable angina pectoris （UAP） and its clinical significance. Methods Sixty - two patients with UAP and sixty healthy controls were enrolled in the study. The UAP patient group was subdivided into high - middle - and low - risk groups （ n = 20, 22 and 20 repectively）. The HRT, including its turbulence onset （ TO ） and turbulence slope （TS） were determined by using digitized Hoher recordings. Results Compared to that in control group, TO was significantly higher in UAP group [（0.16±0. 33）% vs. （ -1.59±0.70）%, P〈0.01]; TS was significantly lower in UAPgroup [（2.15±0.04） ms/RRI vs. （3.11 ± 0.09） ms/RRI, P 〈 0.05 ]. Compared to that in high -risk group, TO was lower in the low- risk group[（-0.07±0.34） % vs. （0.18±0.15） %, P〈0.01] and TS was higher in the low-risk group [（2.16±0. 22 ） ms/RRI vs. （ 2.03 ± 0.19） ms/RRI, P 〈 0.05 ]. Conclusions HRT is significantly blunted in UAP and shows significant differences between that in low - risk group and high - risk groups. Hence, HRT may become a new predictor for the prognosis and the high risk in patients with UAP.
出处
《徐州医学院学报》
CAS
2008年第3期167-169,共3页
Acta Academiae Medicinae Xuzhou
关键词
窦性心率震荡
心绞痛
不稳定型
动态心电图
危险性评估
自主神经功能
预后
heart rate turbulence
unstable angina pectoris
dynamic electrocardiography
risk assessment
autonomic nervous system activity
prognosis
