摘要
微转移是指非血液系统的恶性肿瘤在发展过程中,被捕获、侵出血管并种植于特定器官且发生增殖的播散肿瘤细胞灶,常伴有间质反应,只有通过组织学检查才能确定。宫颈癌微转移的检测主要采用免疫组织化学及聚合酶链反应或逆转录-聚合酶链反应检测淋巴结、外周血和活检标本中人乳头瘤病毒、鳞状细胞癌抗原以及血管内皮细胞生长因子C的表达。
Micrometastasis describes the condition associated with proliferation of disseminated tumor cells,which can invade out of vessels and can be captured,and planted in specific organs accompanyed by stromal reaction,which only can be definited by histological examination.Micrometastasis of cervical carcinoma can be detected mainly by detecting human papilloma virus,squamous cell carcinoma antigen and the expression of endothelial cell growth factor C in lymphaden,peripherall blood and biopsy specimen by immunohistochemistry and PCR(or RT-PCR)assay.
出处
《医学综述》
2008年第6期841-843,共3页
Medical Recapitulate
关键词
宫颈肿瘤
微转移
鳞状细胞癌抗原
Cervical carcinoma
Micrometastasis
Squamous cell carcinoma antigen