Avastin在眼科中的应用被引量：16

Application of Avastin in ophthalmology

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摘要 Avastin-阿瓦斯汀(Bevacizumab)是重组的人源化单克隆抗体,与人血管内皮生长因子(vascularendothelial growth factor,VEGF)结合并阻断其生物活性,从而抑制新生血管的生成。目前,Avastin在肿瘤科得到了广泛应用,而且在治疗眼科新生血管性疾病也取得了很好的疗效。 Bevacizumab （Avastin） is a full-length humanized murine monoclonal antibody combined with VEGF molecule against its function, so Avastin inhibits neovascularization. Now it is not only widely available in the treatment of metastasis but also has been reported good results for the treatment of neovascularization.

作者李灵席新华

机构地区中南大学湘雅二医院眼科

出处《国际眼科杂志》 CAS 2008年第3期582-583,共2页 International Eye Science

关键词阿瓦斯汀血管内皮生长因子新生血管 Avastin VEGF neovascularization

分类号 R77 [医药卫生—眼科]

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参考文献16

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