摘要
目的探讨经额微侵袭治疗高血压性脑出血的临床效果。方法对临床确诊为高血压脑出血、出血量在50mL以下、出血部位在基底节区的患者70例,随机分为经额微侵袭穿刺组(手术组)和保守治疗组(对照组)各35例。手术组中神经功能障碍表现为偏瘫35例,失语22例;保守组偏瘫33例,失语20例。手术病例均在CT定位下行经额穿刺引流手术,术后用尿激酶清除残留血肿。对照组采用常规药物治疗。结果随访3个月,手术组患者重残率(26%)明显低于对照组(54%),神经功能恢复,手术组偏瘫恢复率为74%(治愈+好转),高于对照组48%(P<0.05)。两组在失语表现无显著差异(P>0.05)。结论经额微侵袭治疗高血压性脑出血,创伤小,操作方便,时间短,临床疗效显著,对中等量以下脑出血(<50mL)是一种有效的治疗方法。
Objective To explore the effect of minimally invasive treatment for hypertensive intracerebral hemorrhage via a transfrontal approach. Methods Seventy patients, who were confirmed as hypertensive intracerebral hemorrhage in basal ganglia area with blood loss below 50 ml,were divided into two groups：the minimally invasive treatment group（ n = 35, puncture group）and the conservative treatment group （n = 35, control group）. In the puncture group , 35 patients were hemiparalysis,22 lost word; in the control group, 33 patients were hemiparalysis, while 20 lost word. All cases received the operation with CT location. Remained hematoma was eliminated with urokinase after operation. The control group received normal medicine treatment. Results After 3-month follow-up,the severe disability rate of puncture group （26%） was significantly lower than that of the control group （ 54% ） , neural functional recovery were observed. The hemiparalysis recovery rate of puncture group reached 74% （ including the recovery and improved cases ） , higher than that of the control group （48%）. There was no significant difference in the symptom of losing word between two group （P 〈 0.05 ）. Conclusion Minimally invasive treatment for hypertensive intracerebral hemorrhage via a transfrontal approach is of certain efficacy ,easy operation and less time ,especially for the cases whose blood loss below 50 mL.
出处
《微创医学》
2008年第1期20-22,共3页
Journal of Minimally Invasive Medicine
关键词
高血压性脑出血
微侵袭
尿激酶
Hypertensive intracerebral hemorrhage
Minimally invasive
Urokinase
