摘要
目的:评价黛力新对改善伴有情感障碍慢性紧张型头痛(CTH)患者焦虑及抑郁指数的效果。方法:60例患者随机分为黛力新组(黛力新、鲁南贝特和硫必利),对照组(鲁南贝特和硫必利),疗程6周;于治疗前及治疗后2、4、6周末,用汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评价患者焦虑和抑郁指数,行重复测量方差分析和多元方差分析。结果:HAMA和HAMD评分均随时间变化而变化(HAMA:F=501.073:HAMD:F=1123.157,均P<0.001),而且时间与分组均有交互作用,即组间评分均随时间变化趋势而不同(HAMA:F=191.855;HAMD:F=152.491,均P<0.001)。结论:黛力新对改善伴有情感障碍CTH患者的焦虑及抑郁指数较常规止痛剂效果好。
Objective To evaluate the efficacy of deanxit in chronic tension headache （CTH） patients associated with affective disorder on anxiety and depression index. Methods Sixty patients enrolled were randomly divided into deanxit group and control, each group has 30 patients. The patients in deanxit group were treated with Deanxit, Paracetamol, Chlorzoxazone Dispersible and Tiapride for 6 weeks, while the patients in control group were only treated with Compound Chlorzoxazone and Tiapride for 6 weeks.The patients were scored on anxiety and depression index according to Hanmierdun Anxiety Scale （HAMP）and Hanmierdun Anxiety scale （HAMA）before and 2, 4, and 6 weeks after treatment. Then, the results were evaluated by repeated measurement of variance analysis and multivariate analysis of variance. Results HAMA and HAMD grades varied with time （HAMA：F=501.073, HAMD：F=1123.157, each P〈0.001）, and there was a interaction of time with group division, that is, in the same group, the scores were different with time （HAMA：F=191.855, HAMD：F=152.491, each P〈0.001） ; Conclusion In CTH patients associated with affective disorder, the therapeutic effect of Deanxit is much better than general analgetics on improving anxiety and depression index.
出处
《郧阳医学院学报》
2008年第1期35-38,共4页
Journal of Yunyang Medical College
关键词
黛力新
情感障碍
慢性紧张型头痛
焦虑指数
抑郁指数
重复测量方差分析
Deanxit
Affective disorder
, Chronic tension headache
Anxiety index
Depression index
Repeated measure ment of variance analysis
