摘要
目的:探讨营养疗法在慢性阻塞性肺疾病(COPD)急性发作期治疗中的价值。方法:选择60例急性发作期的COPD患者,随机分为治疗组和对照组,对照组给予抗感染、通畅气道、持续低流量氧疗、纠正心肺功能等常规治疗,治疗组在常规治疗基础上给予营养疗法,并根据BEE(基础能量消耗)估算每日的热量供应,采用复方氨基酸、谷氨酰胺、脂肪乳、白蛋白等静滴2周。结果:治疗组患者在治疗后血清丙、异亮、缬、苏、苯丙氨酸浓度有所上升,血清亮氨酸及血清白蛋白显著上升(P<0.01),对照组上述指标仍明显低于正常。此外,治疗组治疗前后VC占预计值的百分比、FEV1占预计值的百分比和治疗后两组间平均住院时间比较也均有显著性差异(P<0.01),治疗组治疗前后体重比较有差异性(P<0.05)。结论:对COPD急性发作期并营养不良患者给予营养疗法,可改善其营养不良状况,增强患者的免疫力,促进肺功能的改善及缩短住院时间。
Objective：To discuss the value of trophotherapy during acute attack of chronic obstructive pulmonary disc ease（COPD）. Methods：60 cases of COPD during acute attack were randomly divided into treatment group and control group. The control was given usual treatment： antiinfection, airway control, therapy with continuous low discharge oxygen,correction of the function of heart and lungs and so on. In the treatment group the trophotherapy was received On the basis of the usual treatment. The dailt caloric requirement was estimated according BEE, and the compound amino acid,glutamine,fat milk and albumin were dripped intravenously for two weeks. Results： Arter treatment in the treatment group the concentrations of alanine, isolencine,valine,α-amino-β-hydroxybutyric acid and phenylalanine in serum increased and the levels of leucine and albumin increased remarkably （P〈0.01）. The parameters, described above in control group were lower than normal. The percentages of VC and FEV1 in treatment group before and after treatment greatly differed and there was a wide difference in the mean hospitalization days in two groups（P〈0. 01）. Conclusion： During acute attack of COPD the patients should be given trophotherapy. In this case it may improve the nutritional defect condition, increase the immunity, improve the lung function and shorten the hospitalization days.
出处
《医学理论与实践》
2008年第3期268-270,共3页
The Journal of Medical Theory and Practice
关键词
慢性阻塞性肺疾病
急性发作期
营养疗法
Chronic obstructive pulmonary disease,Acute attack, Trophotherapy
