非小细胞肺癌不做淋巴结预防照射的三维适形放疗临床观察
被引量:1
摘要
肺癌是严重威胁人类生命的恶性肿瘤之一,其发病率和死亡率都有逐年上升趋势,总5年生存率为10%-14%。而非小细胞肺癌(NSCLC)占全部肺癌的80%以上,ⅢA、ⅢB期单纯放疗5年生存率仅为5%-7%,中位生存期只有6-11个月。NSCLC治疗失败的主要原因为远处转移和局部复发,而淋巴结引流区是否需要照射目前存在争议。为此笔者初步研究采用三维适形放疗(3DCRT)NSCLC而不进行淋巴结预防照射的可行性。
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2008年第2期148-149,共2页
Chinese Journal of Radiation Oncology
参考文献11
-
1Arriagada R, Le Chevalier T, Rekacewicz E, et al. Cisplatin based chemotherapy in patients with locally advanced non-small cell lung cancer: late analysis of a franeerandomized trial. Proc Am Soc Clin Oncol, 1997,16:446a.
-
2Le Chevalier T, Arriagada R, Tarayre M, et al. Significant effect of adjuvant chemotherapy on survival in locally advanced non-small-cell lung carcinoma. J Natl Cancer Inst, 1992 ,84:58.
-
3王颖杰,王绿化,王鑫,冯勤付,张红星,肖泽芬,殷蔚伯.91例非小细胞肺癌三维适形放疗的临床分析[J].中华放射肿瘤学杂志,2005,14(4):241-244. 被引量:49
-
4Emami B, Mirkovic N, Scott C, et al. The impact of regional nodal radiotherapy (dose/volume) on regional progression and survival in unresectable non-small cell lung cancer: an analysis of RTOG data. Lung Cancer, 2003,41 :207-14.
-
5Rosenzweig KE, Sim SE, Mychalczak B, et al. Elective nodal irradiation in the treatment of non-small-cell lung cancer with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys, 2001,50:681-685.
-
6Hayman JA, Martel MK, Ten Haken RK, et al..Dose escalation in non-small-cell lung cancer using three-dimensional conformal radiation therapy: update of a phase Ⅰ trial. J Clin Oncol, 2001,19:127- 136.
-
7Chen M, Hayman JA, Ten Haken RK, et al. Long-term results of high-dose conformal radiotherapy for patients with medically inoperable T1-3N0 non-small-cell lung cancer: is low incidence of regional failure due to incidental nodal irradiation? Int J Radiat Oncol Biol Phys, 2006,64:120-126.
-
8Armstrong J, Raben A, Zelefsky M, et al. Promising survival with 3- dimensional conformal radiation therapy for NSCLC. Radiother Oncol, 1997,44 : 17-22.
-
9Bradley JD, Graham MV, Winter KW. Acute and late toxicity resuits of RTOG 9311 : a dose escalation study using 3D conformal radiation therapy in patients with inoperable non-small cell lung cancer. Int J Radiat Oncol Biol Phys, 2003,57:S137-S138.
-
10Bradley J, Graham MV, Winter K, et al. Toxicity and outcome resuits of RTOG 9311 : a phase Ⅰ-Ⅱ dose-escalation study using three- dimensional conformal radiotherapy in patients with inoperahle non-small-cell lung carcinoma. Int J Radiat Oncol Biol Phys, 2005,61 : 318-328.
二级参考文献11
-
1李连弟,鲁凤珠,张思维,牧人,孙秀娣,皇甫小梅,孙杰,周有尚,欧阳宁慧,饶克勤,陈育德,孙爱明,薛志福,夏毅.中国恶性肿瘤死亡率20年变化趋势和近期预测分析[J].中华肿瘤杂志,1997,19(1):3-9. 被引量:868
-
2Rowell NP, Williams CJ. Radical Radiotherapy for stage Ⅰ / Ⅱ non-small cell lung cancer in patients not sufficiently fit for or declining surgery (medically inoperable ). The Cochrane Library,2001,2:1-11.
-
3Perez CA, Stanley K, Rubin P,et al.A prospective randomized study of various irradiation doses and fractionation schedules in the treatment of noperable non-oat cell carcinoma of the lung: preliminary report by RTOG. Cancer, 1980,45: 2744-2753.
-
4Perez CA, Pajak TF, Rubin P, et al. Long-term observations of the patterns of failure in patients with unresectable nonoat cell carcinoma of the lung treated with definitive radiotherapy: report by the RTOG. Cancer,1987,59:1874-1881.
-
5Sibley GS, Mundt AJ, Shapiro C, et al. The treatment of stage Ⅲ non-small cell lung cancer using high dose conformal radiothetapy. Int J Radiat Oncol Biol Phys, 1995,33:1001-1007.
-
6Armtrong J, Raben A, Zelefsky M, et al. Promising survival with 3-dimensional conformal radiation therapy for NSCLC. Radiother Oncol,1997,44:17-22.
-
7Sim S, Rosenzweig KE, Schindelheim R, et al. Induction chemotherapy plus three-dimensional conformal radiation therapy in the definitive treatment of advanced non-small cell lung cancer. Int J R adiat Oncol Biol Phys,2001,51:660-665.
-
8Bradley JD, Ieumwananonthachai N, Purdy JA. et al. Gross tumor volume, critical prognosic factor in patients treated with three-dimensional conformal radiation therapy for non-small cell lung carcinoma. Int J Radiat Oncol Biol Phys, 2002,52:49-57.
-
9Hazuka MB,Turrisi AT,Martel MK, et al. Dose escalation in Non-small cell lung cancer using 3-dimensional conformal radiation therapy treatment planning: preliminary results of phase Ⅰ study. Proc Am Soc Clin Oncol, 1994,13:337.
-
10Socinski MA, Morris DE, Halle JS, et al. Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage ⅢA and Ⅲ B non-small-cell lung cancer: a dose-escalation phase I trial. J Clin Oncol,2004,22:4341-4350.
共引文献48
-
1李以元.31例局部晚期非小细胞肺癌经新辅助化疗和三维适形放疗的临床疗效及安全性分析[J].医学信息(医学与计算机应用),2014,0(5):168-168.
-
2周诚忠,夏炎春,夏海波.三维适形放射治疗老年非小细胞肺癌60例[J].东南国防医药,2009,11(1):20-21. 被引量:1
-
3湛永滋,黄昌杰,黄剑峰.非小细胞肺癌三维适形放射治疗的临床研究[J].肿瘤学杂志,2009,15(12):1073-1075. 被引量:1
-
4周诚忠,夏炎春,夏海波.老年非小细胞肺癌50例三维适形放疗的临床分析[J].肿瘤研究与临床,2007,19(z1). 被引量:2
-
5林宇,郁志龙.非小细胞肺癌三维适形放疗新进展[J].内蒙古医学杂志,2006,38(3):263-266. 被引量:3
-
6王纪青,刘松雷,李晋生,李刚,杨继红.后期大分割三维适形放射治疗非小细胞肺癌临床疗效观察[J].临床医药实践,2006,15(5):360-361.
-
7江启安,陈庆,张抒雁,李家敏,申文江.非小细胞肺癌质子射线放射治疗靶区及正常组织剂量分布的研究[J].中华放射医学与防护杂志,2006,26(6):610-613. 被引量:5
-
8陈梓宏,余忠华,赖振南,梁荣,王镇南.三维适形放疗同步化疗治疗局部晚期非小细胞肺癌的临床观察[J].广东医学院学报,2007,25(2):150-152. 被引量:2
-
9郭跃信,李国文.甘氨双唑钠对非小细胞肺癌三维适形放疗的增敏研究[J].中国医师进修杂志(内科版),2007,30(6):25-27. 被引量:2
-
10冯勤付,陈雪松.局部晚期非小细胞肺癌的放疗进展[J].中华放射肿瘤学杂志,2007,16(4):317-320. 被引量:8
同被引文献8
-
1傅小龙.放疗在非小细胞肺癌治疗中地位和研究进展[J].中国癌症杂志,2005,15(3):217-223. 被引量:30
-
2林宇,郁志龙.非小细胞肺癌三维适形放疗新进展[J].内蒙古医学杂志,2006,38(3):263-266. 被引量:3
-
3胡松柳,徐向英.非小细胞肺癌三维适形放射治疗的研究现状[J].实用肿瘤学杂志,2006,20(5):448-451. 被引量:14
-
4李洪升,李宝生.非小细胞肺癌放射性肺损伤的研究进展[J].中华肿瘤防治杂志,2007,14(18):1437-1439. 被引量:24
-
5孙建湘,莫清华,周隆军,廖彬生.三维适形加量放疗联合化疗治疗非小细胞肺癌的临床观察[J].中华肿瘤防治杂志,2007,14(24):1889-1890. 被引量:11
-
6王静,王平,庞青松.放射性肺损伤的剂量体积关系研究现状[J].中华放射肿瘤学杂志,2008,17(2):155-157. 被引量:9
-
7汪洋,施学辉,姚伟强,吴根娣,郭小毛,王颖.连续加速超分割与后程加速超分割治疗食管癌[J].中华放射肿瘤学杂志,2000,9(3):152-155. 被引量:59
-
8赵充,陈明,吴少雄,曾祥发,卢泰祥,崔念基,钱剑扬.逐步递量加速超分割放射治疗局部晚期鼻咽癌[J].中国癌症杂志,2000,10(5):408-410. 被引量:13
-
1于甬华,罗立民,陈延条,于金明,梁超前,田世禹,孙新东,韩俊庆.小细胞肺癌脑预防照射适应证的临床探讨[J].中华结核和呼吸杂志,2000,23(12):739-739. 被引量:2
-
2庆明轩,李国文,田爱玲.少年鼻咽癌颈部预防照射后诱发甲状腺癌一例[J].河南医科大学学报,1995,30(1):91-92. 被引量:1
-
3李国良.未分化小细胞肺癌的放疗加联合化疗[J].中华放射肿瘤学杂志,1990,0(3):33-33.
-
4吴湘玮,金性江,胡自省.213例女性肺癌综合治疗分析[J].中华放射肿瘤学杂志,1990,0(4):52-53.
-
5邓永宁,文蕾.结肠镜检查诊断大肠癌17例体会[J].现代医药卫生,2006,22(10):1523-1524.
-
6沈文斌(综述),祝淑钗(审校),王展宏(校对).局限期小细胞肺癌脑预防照射研究进展[J].中国肿瘤临床,2006,33(16):956-959. 被引量:3
-
7柳影(综述),程颖(审校).小细胞肺癌诊断与治疗[J].国际肿瘤学杂志,2008,35(7):509-512.
-
8曾强,李新娉,杜晓宇.局部晚期鼻咽癌同步放化疗与单纯放疗的疗效分析[J].中国癌症防治杂志,2016,8(4):252-254. 被引量:2
-
9史艳春,王艳,荆结线.结直肠癌信号通路及相关基因的研究进展[J].中华生物医学工程杂志,2016,22(5):433-438. 被引量:2
-
10马文,张祥静.人类生命的希望[J].科技潮,2000(5):56-58.