结核感染与Toll样受体
摘要
结核分枝杆菌感染仍是全球性的健康难题。迄今，全世界约有20亿人感染结核，占总人口数的1／3，并导致每年220万例患者死亡。与大多数感染不同，结核杆菌可在人体内长期潜伏而不被清除。感染人群中只有1／10会发展为活动性结核。疾病的发展不仅取决于菌株毒力，且与个体的免疫状态密切相关。近年来，在巨噬细胞表面表达的Toll样受体（toll—like receptor，TLR）家族受到越来越多的关注，其对于巨噬细胞与结核杆菌相互作用的影响已在众多研究中得以揭示。
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2008年第2期122-125,共4页
Chinese Journal of Infectious Diseases
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