摘要
目的研究子宫内膜异位症患者组织中前列腺素PGE2、TXB2与患者痛经强度的相关性。方法对子宫内膜异位症患者痛经强度进行评分,并采用免疫组织化学SABC法检测PGE2、TXB2在其组织中的表达。结果子宫内膜异位症异位病灶中PGE2、TXB2表达与痛经强度评分呈正相关。结论子宫内膜异位症异位病灶局部PGs合成异常增多是导致痛经的重要原因之一。
Objective To measure the levels of prostaglandins（PGE2,TXB2） in biopsy specimens from patients with endometriosis,and explore the relationship between prostaglandin level and the severity of pain, Methods The expression of PGE2,TXB2 protein was detected with immunohistochemistry（SABC）in 30 biopsy specimens from patients with endometriosis, Results A positive correlation was found between the severity of dysmenorrhea and the level of PGE2 and TXB2 in endometriosis, Conclusion The dysfunctional increase of prostaglandins in the uterus may be the important cause for dysmenorrhea in patients with endometriosis.
出处
《中国现代医生》
2008年第5期86-87,共2页
China Modern Doctor
