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过敏性紫癜患儿IL-6、IL-8及TNFα水平研究

THE OBSERVATION OF IL-6,IL-8 AND TNFα LEVELS IN SERUM FROM PATIENTS WITH HYPERSENSITIVITY PURPURA
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摘要 采用ELISA双抗体夹心法,检测了36例过敏性紫癜患儿血清IL-6、IL-8和TNFα水平。结果表明,过敏性紫癜患儿血清TNFα含量明显高于对照组,IL-6与IL-8水平升高不明显。提示,在过敏性紫癜的发病过程中TNFα起了重要病理作用。 The levels of IL 6,IL 8 and TNFα in serum of 36 patients with hypersensitivity purpura (HSP) was measured using sandwich ELISA. The results showed that the level of TNFα in serum was significantly increased in 36 patients with HSP compared with that in normal controls.The levels of IL 6 and IL 8 were not obviously higher in the patients than those in the controls.These results suggest that TNFα may play a certain role in the pathogenesis of HSP.
出处 《滨州医学院学报》 1997年第5期427-427,共1页 Journal of Binzhou Medical University
关键词 过敏性紫癜 IL-6 IL-8 TNFΑ HSP IL 6 IL 8 TNFα
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