摘要
目的观察术中应用硫酸镁对颅内血肿患者早期神经功能的影响。方法选择80例颅内血肿行开颅手术治疗的患者,随机分为二组:治疗组(硫酸镁16ml)和对照组。记录二组患者手术前后3d、1周、2周、4周Barthel指数、独立功能评定(FI M)及哥拉斯格预后评分(GOS)。结果治疗组Barthel指数好于对照组(P<0.05),但二组FI M及GOS比较差异无统计学意义(P>0.05)。结论术中应用硫酸镁对颅内血肿患者术后早期神经功能的改善有一定疗效。
Objective To observe the effect of intraoperative administration of magnesium sulfate on neurological function in the early stage of postoperative period in patients with intracranial hematoma. Methods 80 patients with intracranial hematoma who received craniotomy were divided into therapy group （16 ml magnesium sulfate intravenously and intraoperatively） and control group randomly. Barthe index, FIM and GOS of all the patients were meas- ured after 3d,1w,2w,4w, respectively. Results Barthe index in therapy group was sign/ficantly better than that in control group （P〈0.05）. FIM and COS in therapy group was better than that in control group, but it had not significance （P〉0.05）. Conclusion Intraoperative administration of magnesium sulfate could partly improve neurological function in early stage of postoperative period in patients with intracranial hematoma.
出处
《中国煤炭工业医学杂志》
2008年第2期143-145,共3页
Chinese Journal of Coal Industry Medicine
关键词
硫酸镟
颅内血肿
神经功能
预后
magnesium sulfate
intracranial hematoma
neurological function
prognosis
