氯诺昔康在围手术期的应用进展被引量：7

Advancement of perioperative application of lornoxicam

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摘要氯诺昔康是一种新型的非甾体类抗炎药,其不仅可抑制环氧化酶的活性,还可抑制术后的免疫损伤,其超前镇痛、术中及术后的镇痛疗效与阿片类药物相似,可明显减少阿片类镇痛药物的用量。同时氯诺昔康具有半衰期短、不良反应少、耐受性良好等优点,在围手术期可提供快速而稳定的镇痛效果。 Lomoxicam is a new non-steroidal antiinflammatory drug, it can inhibit the activity of cyclooxygenases and the immunologic injury afteroperation. Its efficacies on preoperative, operative period and postoperative analgesia are similar to those of opioid. Lomoxicam can decrease the dosage of opioid drugs and has the good qualities of short half-life, few adverse effects and satisfactory tolerance. Lomoxicam can provide rapid and stable analgesic effect in perioperative phase.

作者陈小非郭建荣

机构地区宁波大学医学院附属李惠利医院麻醉科

出处《中国临床药理学与治疗学》 CAS CSCD 2008年第1期16-20,共5页 Chinese Journal of Clinical Pharmacology and Therapeutics

关键词氯诺昔康围手术期镇痛非甾体抗炎药 lomoxicam perioperative phase analgesia non-steroidal anti-inflammatory drug

分类号 R614 [医药卫生—麻醉学]

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参考文献4

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