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脂联素在急性心肌梗死患者中的表达及意义 被引量:4

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摘要 目的观察血浆脂联素(APN)在急性心肌梗死(AMI)中的表达变化及意义。方法选择AMI患者20例,不稳定型心绞痛组(UAP)20例,稳定型心绞痛(SAP)20例及正常对照组20例,采血测定血浆APN浓度、低密度脂蛋白胆固醇(LDL-C)浓度、总胆固醇(TC)和甘油三酯(TG)浓度。比较4组间血浆APN、LDL-C、TC和TG水平,并比较APN与LDL-C、TG及TC水平的相关性。结果AMI组APN水平显著低于UAP组、SAP组及对照组,UAP、SAP组APN水平也显著低于正常对照组;各组中APN水平与LDL-C水平呈负相关(p<0.05);各组间TG浓度比较无统计学差异;AMI组TC浓度最高,明显高于UAP、SAP及对照组。结论AMI和心绞痛患者APN水平下降而AMI患者更低,各组脂联素水平与LDL-C水平呈负相关,表明APN可能是冠心病的一种重要保护因子。
出处 《浙江实用医学》 2008年第1期1-2,共2页 Zhejiang Practical Medicine
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