摘要
目的:研究银荆感冒颗粒的解热作用。方法:将54只SD大鼠随机分成模型组,正柴胡颗粒组,扑热息痛组及银荆感冒颗粒小、中、大剂量组,每组9只。末次给药后,大鼠背部皮下注射2,4-二硝基苯酚,测量大鼠体温的变化情况;大鼠后脚两爪脚跖皮下注射角叉莱胶悬液,测量其肛温的变化情况。结果:(1)银荆感冒颗粒小、中、大剂量组对2,4-二硝基苯酚所致大鼠发热解热作用的持续时间分别为120、150、180 min以上;(2)银荆感冒颗粒小、中、大剂量组对角叉莱胶所致大鼠发热的解热作用的持续时间分别为4、5、6 h。结论:银荆感冒颗粒具有较好的解热作用。
Objective To study the effect of Yinjingganmao grains to relieve fever. Methods （ 1 ） The rats were given Yinjingganmao grains for 7 days. On the last day, the rats were injected subcutaneouly on their back with dinitrophenol and the body temperature of rat was measured. （2）The rats were given Yinjingganmao grains for 7 days. On the last day, the rats were injected subcutaneouly on the foot plate of crus curvilineum with SN-263 and the anus temperature of rat was measured. Results Yinjingganmao grains relieved fever caused by dinitrophenol lasting 120,150 and 180 min respectively in the three groups, while fever caused by SN-263 was relieved for 4,5,6 h respectively. Conclusion Yinjingganmao gains significantly relieve fever.
出处
《东南大学学报（医学版）》
CAS
2008年第1期10-12,共3页
Journal of Southeast University(Medical Science Edition)
基金
江苏省中医药管理局资助项目(H05027)
