摘要
藏药唐古特青兰水提液ip给药,可显著延长断头小鼠张口动作的持续时间和结扎双侧颈动脉的存活时间,显著延长小鼠尾静脉注射空气后的大口喘气开始时间和吸气停止时间,还有一定延长利多卡因中毒小鼠存活时间的趋势。另外该药对模拟高原缺氧环境所造成的大鼠脑组织病理损伤具有一定的保护作用。提示该药具有抗动物脑缺血缺氧作用。
The aqueous extracts ip of Dracocephalum tanguticum Maxim (DtM), a Tibetan medicine, prolong significantly decapitaion-induced gasping duration in mice and the survival time of mice ligated bilateral carotid (P >0. 01). DtM prolong also the primal gasping in mice after injecting the air into the coccygeal vein (P>0. 01) and the survival time in mice poisoned by Lidocaine (P>0. 05). In addition, DtM is possessed of protecting against the pathologic lession of brain in rats under stimulating high altitude hypoxic condition. The results suggest that DtM has a antianoxic effects on mice
出处
《中药材》
CAS
CSCD
1997年第4期198-200,共3页
Journal of Chinese Medicinal Materials
基金
青海省卫生厅青年科技基金
关键词
藏药
唐古特青兰
抗脑缺氧
药理
Tibetan Medicine
Dracocephalum tanguticum
Brain Anoxia
