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吡喹酮抗血吸虫作用机制研究进展 被引量:8

Progress of research on mechanism of praziquantel against schistosome
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作者 李欣 夏超明
出处 《中国血吸虫病防治杂志》 CAS CSCD 2008年第1期78-80,共3页 Chinese Journal of Schistosomiasis Control
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  • 1杨藻宸.医用药理学[M].4版.北京:人民卫生出版社,2005:1026-1028.
  • 2Redman CA, Robertson A, Fallon PG, et al. Praziquantel, An urgent and exciting challenge[J]. Parasitol Today, 1996,12(1) : 14- 20.
  • 3Richards MW, Butcher AJ, Dolphin AC. Ca^2+ channel beta subunits: structural insights AID our understanding [ J ]. Trends Pharmaeol, 2004,25 (12) : 626-632.
  • 4Kohn AB, Anderson PA, Roberts-Misterly JM, et al. Schistosome calcium channel beta subunitst Unusual modulatory effects and potential role in the action of the antisehistosomal drug praziquantel[J]. J Biol Chem, 2001,276 (40): 36873-36876.
  • 5Greenberg RM. Are Ca^2+ channels targets of praziquantel action [J]? Int J Parasitol,2005,35(1): 1-9.
  • 6De Waard MD, Pragnell M, Campbell KP. Ca^2+ channel regulation by a conserved β subunit domain[J]. Neuron, 1994,13( 1): 495-503.
  • 7Keel KD, Hume JR, Zhong J. Regulation of cardiac and smoothmuscle Ca^+ channels (Cav1. 2a, b) by protein kinases[J]. Am J Physiol Cell Physiol, 2001,281(6) : C1743-C1755.
  • 8Kohn AB, Roberts-Misterly JM, Anderson PA, et al. Specific residues in the beta interaction domain of a sehistosome Ca^2+ channel beta subunit are key to its role insensitivity to the antischistosomal drug praziquantel[J]. Parasitology,2003, 127(4): 349- 356.
  • 9Kohn AB, Roberts-Misterly JM, Anderson PA, et al. Creation by mutagenesis of a mammalian Ca^2+ channel beta subunit that confers praziquantel sensitivity to a mammalian Ca^2+ ehannel[J]. Int J Parasitol, 2003,33 (12) : 1303-1308.
  • 10Valle C, Troiani AR, Festucci A, et al. Sequence and level of endogenous expression of calcium channel beta subunits in Schistosorna rnansoni displaying different susceptibilities to praziquantel[J]. Mol Biochem Parasitol,2003, 130(2): 111-115.

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