摘要
为了探讨原发性胃恶性淋巴瘤（ＰＧＭＬ）与幽门螺杆菌（Ｈｐ）感染的相关性，收集３９例ＰＧＭＬ与２２例淋巴性胃炎、３２例Ｈｐ无关疾病的胃粘膜作病例对照研究；Ｈｐ感染的确定采用改良的Ｇｉｅｍｓａ染色；ＰＧＭＬ的分类结合组织学和免疫组化染色。结果：ＰＧＭＬ组Ｈｐ检出率为８７．１８％，显著高于对照的６３．６４％及５３．１３％（Ｐ＜０．００５）。粘膜相关淋巴样组织（ＭＡＬＴ）来源的淋巴瘤占９２．３１％，Ｈｐ检出率达８６．１１％，瘤周慢性活动性胃炎及淋巴滤泡检出率分别为８４．６２％及５６．４１％。组织学检测的初步结论为：胃Ｂ细胞ＭＡＬＴ淋巴瘤与Ｈｐ感染相关。
In order to investigate the relationship between primary gastric malignant lymphoma (PGML) and helicobacter pylori (Hp) infection, the gastric mucosa of 39 cases of PGML and 22 cases of lymphocytic gastritis, 32 cases of Hp unrelated diseases was collected in this case control study. Hp infection was confirmed by modified Giemsa stain; PGML was classified by Isaacson's classification. Result: The Hp detecting rate of PGML was 87.18%, which was significantly higher than that of control groups that was 63.64%, 53.13% respectively ( P <0.005). Mucosa associated lymphoid tissue (MALT) type was accounted for 92.31% of PGML cases with Hp detecting rate 86.11%. In surrounding chronic active gastritis and lymphoid follicles Hp were detected in 84.62%, 56.41% cases respectively. In conclusion: histology shows a good relationship between B cell gastric MALT lymphoma and Hp infection.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1997年第7期442-445,共4页
Chinese Journal of Internal Medicine
基金
四川省科学技术委员会科研基金
关键词
淋巴瘤
胃肿瘤
幽门螺杆菌
相关性
Helicobacter pylori Lymphoma, mucosa associated lymphoid tissue
