摘要
为确定致病菌和传染源,采用随机扩增多态DNA指纹图技术对医院内感染的14例新生儿进行病原流行病学分析。结果:患儿与医务人员鼻腔的华纳葡萄球菌菌株的DNA指纹图谱完全一致。结论:从分子生物学角度证明此次感染病原菌为华纳葡萄球菌,传染源与医务人员有关。
In one recent episode of staphylococcus infection of newborn in the hospital, the authors sampled, cultured and investigated from different circumstances to identify the source and epidemiology of the infection. Randomly amplified polymorphic DNA (RAPD) technique was used in this study. The results showed that DNA fingerprinting map of the strains of S. warneri isolated from the nasal cavity of infected infants was identical to that from the medical staff. The authors conclude that the infection was caused by S. warneri and that the source of infection was associated with the medical staff.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
1997年第7期381-383,共3页
Chinese Journal of Pediatrics
关键词
葡萄球菌感染
分子流行病学
医院内感染
新生儿
Infant, newborn Staphylococcal infection Cross infection DNA fingerprinting